Atrial Myxoma and Bone Changes: A Paraneoplastic Syndrome?

Smith, Marcus J.; Chaudhry, Muhammad; Humphrey, Mary Beth; Lozano, Pedro

doi:10.1111/j.1540-8191.2011.01277.x

Cited by 5 publications

(3 citation statements)

References 9 publications

(8 reference statements)

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“…Typically, cardiac myxoma symptoms arise from flow obstruction, embolization, and the production of interleukin-6 by tumor cells; in addition, symptoms vary based on tumor size, location, and texture. Interleukin-6 release causes systemic symptoms or paraneoplastic syndrome such as fever, weight loss, and arthralgia [ 4 , 5 ]. Furthermore, symptoms may be position-specific, such as trepopnea, owing to mass motion hindering blood flow.…”

Section: Discussionmentioning

confidence: 99%

A polo ball in the right atrium, importance of echocardiographic characteristics of intracardiac myxomas: a case report

Hamdan,

Alam,

Kossaify

2023

J Med Case Reports

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Background Myxomas are the most prevalent type of heart tumors, mainly occurring in the left atrium, with approximately 20% of cases found in the right atrium. Timely diagnosis and appropriate management of myxomas are crucial for favorable outcomes and to minimize complications. Case presentation A 77-year-old Asian male with no significant medical history presented with intermittent trepopnea and palpitations. Physical examination revealed regular heart sounds and no other relevant findings. A transthoracic echocardiogram showed a large, round-shaped, smooth-edged mass with diameter of 86 mm, occupying most of the right atrium. Mild tricuspid flow obstruction and mild left ventricular systolic dysfunction were also observed. Cardiac tomography confirmed the size, smooth edges, and showed microcalcifications of the mass, with no invasion of surrounding tissues. Surgical intervention successfully removed the spheroid mass, leading to the alleviation of symptoms. Histopathology confirmed the myxoma nature of the mass. A comprehensive discussion based on relevant medical literature is provided, with emphasis on echocardiographic characteristics of the mass with relation to potential embolic disease. Conclusion This case shows an atypical presentation of an exceptionally large myxoma in the right atrium, resembling the size of a polo ball, in a patient presenting with supraventricular arrhythmia and trepopnea. Early diagnosis and appropriate management played a vital role in achieving a successful outcome for the patient.

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Section: Discussionmentioning

confidence: 99%

A polo ball in the right atrium, importance of echocardiographic characteristics of intracardiac myxomas: a case report

Hamdan,

Alam,

Kossaify

2023

J Med Case Reports

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“…It is likely that this occurred in our described case. 6 Paraneoplastic syndrome can present with varying manifestations, including chorea. However, PNS related to cancerous and noncancerous masses in the pediatric population is extremely rare.…”

Section: Discussionmentioning

confidence: 99%

“Chorea”: A Unique Presentation of Left Atrial Myxoma in a Pediatric Patient

Chikkabyrappa

Tretter

Vishwanath

et al. 2017

World J Pediatr Congenit Heart Surg

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We report an unusual presentation of a large left atrial myxoma in an eight-year-old girl who presented with the sudden onset of chorea. This case illustrates the fact that the presentation of chorea in nonendemic areas for rheumatic fever should raise suspicion for a myxoma. The chorea resolved soon after removal of the myxoma, supporting the hypothesis of an immune-mediated mechanism, or manifestation of paraneoplastic syndrome secondary to the myxoma.

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“…One recent case report of 5-year history of visual loss, vertigo, ataxia, tinnitus, and bone lesions that resolved after diagnosis and resection of the atrial myxoma has raised a possibility of it causing a paraneoplastic syndrome. [8] Atrial myxoma can get infected when vegetations may be seen attached to its surface. [9]…”

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confidence: 99%

Is the heart truly noble?

Yusuf¹

2013

South Asian J Cancer

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Atrial Myxoma and Bone Changes: A Paraneoplastic Syndrome?

Cited by 5 publications

References 9 publications

A polo ball in the right atrium, importance of echocardiographic characteristics of intracardiac myxomas: a case report

A polo ball in the right atrium, importance of echocardiographic characteristics of intracardiac myxomas: a case report

“Chorea”: A Unique Presentation of Left Atrial Myxoma in a Pediatric Patient

Is the heart truly noble?

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