Atrial myxoma: a rare cause of hemiplegia in children

Onubogu, Uchenna; West, Boma Awoala; Orupabo-Oyan, Boma

doi:10.5830/cvja-2016-093

Cited by 9 publications

(10 citation statements)

References 10 publications

(9 reference statements)

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“…These findings suggest the protective role of vitamin D [95] (Figure 2). However, no independent association was found between low vitamin D levels and AF after coronary artery bypass surgery [96]. Similarly, the Atherosclerosis Risk in Communities (ARIC) study did not find any significant association between low levels of vitamin D and incident AF in a community-based cohort and in a meta-analysis of prospective studies comprising 12,303 subjects.…”

Section: Cardiac Diseasesmentioning

confidence: 99%

Role of Vitamin D in Cardiovascular Diseases

Rai

Agrawal

2017

Endocrinology and Metabolism Clinics of North America

118

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Vitamin D is critical in mineral homeostasis and skeletal health, and plays regulatory role in non-skeletal tissues. Vitamin D deficiency is associated with chronic inflammatory diseases, including diabetes and obesity both being strong risk factors for cardiovascular diseases (CVD). CVD, including coronary artery disease, myocardial infarction, hypertrophy, cardiomyopathy, cardiac fibrosis, heart failure, aneurysm, peripheral arterial disease, hypertension, and atherosclerosis, are major causes of morbidity and mortality worldwide. The association of these diseases with vitamin D deficiency and improvement with vitamin D supplementation suggest its therapeutic benefit. Here, we critically review the recent findings on the association of vitamin D deficiency and CVD.

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Section: Cardiac Diseasesmentioning

confidence: 99%

Role of Vitamin D in Cardiovascular Diseases

Rai

Agrawal

2017

Endocrinology and Metabolism Clinics of North America

118

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“…A key action recommended in the plan to eradicate RHD inAfrica includes appropriate training of health workers to safelyand effectively deliver BPG. 22 The preliminary experience in Zambia suggests that appropriate educational interventions in the setting of drug availability and ready access to medications to treat anaphylaxis can positively impact on rates of BPG usage. Future work will involve the exploration of innovative ways to scale up the RHD control programme, such as the use of electronic training modules, and determination of the impact of these types of interventions on health outcomes, including the incidence of RF and RHD.…”

Section: Discussionmentioning

confidence: 99%

“… 18 - 20 The reasons for this are complex and related to a multitude of interacting factors, including drug supply, pharmaco-economics, health service infrastructure and possibly socio-cultural drivers. 21 Indeed, a recent high-level report outlining the key actions required to eradicate RHD in Africa identified variable supply and suboptimal quality and use of penicillin as some of the major barriers to achievement of this goal, 22 a position endorsed by the World Heart Federation. 23 …”

Section: Introductionmentioning

confidence: 99%

“…In SSA, leading technical authorities, including the Pan-African Society of Cardiology (PASCAR), have advocated the use of BPG for the treatment of streptococcal pharyngitis and the management of RHD to maximise the likelihood of patient compliance with recommended regimens, an approach that has met with success in other low-resource settings. 22 , 24 , 25 There is also evidence that BPG may be more effective than oral penicillin for secondary prophylaxis of RHD and, consequently, it is a commonly recommended therapy. 14 , 26 , 27 …”

Section: Introductionmentioning

confidence: 99%

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A programme to increase appropriate usage of benzathine penicillin for management of streptococcal pharyngitis and rheumatic heart disease in Zambia

Long

Lungu

Machila

et al. 2017

CVJA

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SummaryRheumatic heart disease is highly prevalent and associated with substantial morbidity and mortality in many resourcepoor areas of the world, including sub-Saharan Africa.Primary and secondary prophylaxis with penicillin has beenshown to significantly improve outcomes and is recognisedto be the standard of care, with intra-muscular benzathine penicillin G recommended as the preferred agent by many technical experts. However, ensuring compliance with therapyhas proven to be challenging. As part of a public–privatepartnership initiative in Zambia, we conducted an educationaland access-to-medicine programme aimed at increasing appropriate use of benzathine penicillin for the preventionand management of rheumatic heart disease, according tonational guidelines. The programme was informed early onby identification of potential barriers to the administration ofinjectable penicillin, which included concern by health workers about allergic events. We describe this programme andreport initial signs of success, as indicated by increased useof benzathine penicillin. We propose that a similar approach may have benefits in rheumatic heart disease programmes in other endemic regions.

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“…[3][4][5][6] According to our review of relevant literature, no such cases were reported in in the last 10 years possibly because of a substantial decline in the incidence of rheumatic heart disease. Myxomas are most commonly located in the left atrium, originate from the fossa ovalis, and present with symptoms of thromboembolism [7] or mitral valve outflow obstruction. [8] Constitutional symptoms include fever, weight loss, arthralgias, anemia, elevated globulins and sedimentation rate which could mimic infective endocarditis, particularly with mitral stenosis.…”

Section: Discussionmentioning

confidence: 99%

A rare association of left atrial myxoma with rheumatic mitral stenosis

Vaidya

Devarapally

2016

CRIM

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Primary cardiac tumors are very rare. Atrial myxomas are the most common primary tumors and are commonly located in the left atrium. Myxomas can cause mitral valve inflow obstruction and can present with clinical signs and symptoms of mitral stenosis and the possibility of myxoma should be considered in differential diagnosis of mitral stenosis. Left atrial myxoma is rarely associated with rheumatic mitral stenosis. Transesophageal echocardiography plays a major role in the diagnosis of this tumor. We report a case of an extremely rare association between left atrial myxoma and rheumatic mitral stenosis. Because of its location and mobility, a thrombus in the left atrium may have a similar appearance to left atrial myxoma. However, a careful inspection of features of the left atrial mass may allow a diagnosis of left atrial myxoma. In our case, the site near the atrial septum, heterogeneous echogenicity, and detection of a stalk connecting the myxoma to the atrial septum were inspected. Such findings essentially exclude thrombus.

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Atrial myxoma: a rare cause of hemiplegia in children

Cited by 9 publications

References 10 publications

Role of Vitamin D in Cardiovascular Diseases

Role of Vitamin D in Cardiovascular Diseases

A programme to increase appropriate usage of benzathine penicillin for management of streptococcal pharyngitis and rheumatic heart disease in Zambia

A rare association of left atrial myxoma with rheumatic mitral stenosis

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