Atrial Fibrillation in Atrial Septal Defect

Tikoff, Gerasim; Schmidt, Alexander M.; Hecht, Hans H.

doi:10.1001/archinte.1968.03640050012003

Cited by 14 publications

(3 citation statements)

References 11 publications

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“…Nine per cent of young adults with atrial fibrillation were secondary to congenital heart disease out of which atrial septal defect was the commonest. Atrial fibrillation occurs in approximately 20% of patients with atrial septal defect [ 19 ]. It also occurs in Ebstein anomaly [ 20 ] and post-surgical correction of the ventricular septal defect, tetralogy of Fallot, pulmonary stenosis, and transposition of great arteries.…”

Section: Discussionmentioning

confidence: 99%

Non-Valvular Atrial Fibrillation in Young Adults in Eastern India: A Clinico-Aetiological Retrospective Analysis in a Tertiary Care Hospital

Mohanty¹,

Banerjee²,

Kumar³

et al. 2023

Cureus

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Background: The development of atrial fibrillation adds a lot to the morbidity and mortality of individual patients. The spectrum of non-valvular atrial fibrillation among young adults is less known. The present observational study aims to analyze the clinical-aetiological spectrum of non-valvular atrial fibrillation among young adults between 18 and 40 years of age.Methods: A retrospective observational study was carried out to analyze the clinical-aetiological spectrum of non-valvular atrial fibrillation among young adults less than 40 years of age attending the cardiac outpatient department in a tertiary care hospital in Eastern India over a period of two years. Patients with any form of organic valvular heart disease and patients more than 40 years of age were excluded from the study. One hundred and seventeen patients under 40 years of age were analysed with respect to demographic, aetiological, and clinical profiles.Results: Most common aetiologies behind non-valvular atrial fibrillation in young adults (<40 years) were hypertension (40%) and the presence of left ventricular systolic dysfunction (31%). Thyrotoxicosis, obesity, obstructive sleep apnoea, the presence of congenital heart disease, coronary artery disease, myopericarditis, chronic kidney disease, dyselectronemia, diabetes mellitus, and the presence of chronic obstructive pulmonary disease contributed towards the development of non-valvular atrial fibrillation in the young population in less proportion of cases. Most of the cases were symptomatic with palpitation, shortness of breath, or diaphoresis. Less number of cases (17%) had left atrial thrombus which may be due to early clinical attention with the proper therapeutic anticoagulation regimen.Conclusions: Hypertension and the presence of left ventricular systolic dysfunction contribute to the majority towards the development of non-valvular atrial fibrillation among young adults. Accurate measurement and monitoring of blood pressure among young adults and careful assessment of left ventricular systolic dysfunction with subsequent appropriate management of hypertension and left ventricular systolic dysfunction in young can decrease the burden of non-valvular atrial fibrillation among the young population.

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Section: Discussionmentioning

confidence: 99%

Non-Valvular Atrial Fibrillation in Young Adults in Eastern India: A Clinico-Aetiological Retrospective Analysis in a Tertiary Care Hospital

Mohanty¹,

Banerjee²,

Kumar³

et al. 2023

Cureus

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“…The 17% occurrence of this condition is much higher than other reported series. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] Of particular interest is the finding that 10 of 11 patients with cardiomyopathy were Saudi nationals. The diagnosis of cardiomyopathy (both dilated and hypertrophic types) was based on clinical assessment and confirmed by echocardiography.…”

Section: Cardiomyopathymentioning

confidence: 99%

Atrial Fibrillation: An Analysis of 65 Patients from King Khalid University Hospital

et al. 1986

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A retrospective review of 65 consecutive patient charts with a diagnosis of atrial fibrillation was performed in order to study the prevalence of associated underlying diseases. Rheumatic heart disease was noted in 31%, cardiomyopathy in 17% and arteriosclerotic heart disease in 12%. Atrial fibrillation was paroxysmal in 23 patients (35%) and sustained in 42 (65%) of the patients. Increased left atrial size was an important predictor of sustained atrial fibrillation.

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“…9-12 Repair of the atrial septal defect, however, rarely stops chronic atrial fibrillation once it has persisted for longer than 1 year. [3][4][5][6] Atrial c o m p a r t m e n t surgery based on Moe's multiple wavelet hypothesis 13 is designed to eliminate the atrial fibrillation, restore sinus rhythm, and restore t h e atrial contractility. The procedure divides the atrJ[um into several compartments to re-duce the atrial mass.…”

mentioning

confidence: 99%

Atrial compartment surgery for chronic atrial fibrillation associated with congenital heart defects

Lin¹,

Huang²,

Lin³

et al. 1996

The Journal of Thoracic and Cardiovascular Surgery

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In three adult patients, two with atrial septal defect and one with Ebstein's anomaly, chronic atrial fibrillation was documented for 13, 21, and 3 years, respectively. Atrial compartment surgery was performed for ablation of the atrial fibrillation concomitant with repair of the cardiac defects. The operation was performed with traditional cardiopulmonary bypass and crystalloid cardioplegia myocardial protection. A U-shaped incision was made in the right atrium: a longitudinal incision 1 cm lateral and parallel to the sulcus terminalis, extending along the borders of the atrial septum to 3 cm (upper margin) and 1 cm (lower margin) distant to the tricuspid anulus. Cryolesions of the atrial isthmus between the upper incision margin and the tricuspid valve anulus were created at -60 degrees C for 180 seconds at a time. After the operation, all three patients had restored and maintained normal sinus rhythm during follow-up periods of 32, 16, and 3 months. Doppler echocardiography detected the recovery of atrial contractility in all three patients. Atrial compartment surgery is a simple and effective method for elimination of chronic atrial fibrillation associated with congenital heart defects.

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Atrial Fibrillation in Atrial Septal Defect

Cited by 14 publications

References 11 publications

Non-Valvular Atrial Fibrillation in Young Adults in Eastern India: A Clinico-Aetiological Retrospective Analysis in a Tertiary Care Hospital

Non-Valvular Atrial Fibrillation in Young Adults in Eastern India: A Clinico-Aetiological Retrospective Analysis in a Tertiary Care Hospital

Atrial Fibrillation: An Analysis of 65 Patients from King Khalid University Hospital

Atrial compartment surgery for chronic atrial fibrillation associated with congenital heart defects

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