Atrial fibrillation: current knowledge and recommendations for management*1

Lévy, Samuel

doi:10.1053/euhj.1998.1050

Cited by 276 publications

(77 citation statements)

References 183 publications

(278 reference statements)

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“…12 30 Persistence of AF requires that the depolarising wave fronts must continuously encounter excitable tissue, a circumstance favoured by slow atrial conduction. 31 AF is characterised by re-entry circuits propagating around areas of either fixed or functional conduction block. Functional block is dependent on heterogeneities of cardiac tissue 32 that may be caused by factors such as oedema due to manipulation of the heart at surgery, atrial ischaemia, 33 changes in autonomic tone, 34 35 and inflammatory changes due to pericarditis or cardiopulmonary bypass.…”

Section: Potential Mechanisms Of Benefitmentioning

confidence: 99%

Spontaneous termination of ventricular fibrillation

Calabrò¹,

Luzza²,

Carerj³

et al. 2004

Heart

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Section: Potential Mechanisms Of Benefitmentioning

confidence: 99%

Spontaneous termination of ventricular fibrillation

Calabrò¹,

Luzza²,

Carerj³

et al. 2004

Heart

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“…It may be achieved in 70-80% of patients within 8 h of onset of atrial fibrillation with oral antiarrhythmic agents such as propafenone or flecainide [1] . In atrial fibrillation lasting more than 48 h, the success rates of pharmacological therapy decrease markedly and electrical cardioversion becomes the favoured option and requires proper anticoagulation [1] . Electrical transthoracic cardioversion is able to restore sinus rhythm in 65 to 90% of cases of chronic atrial fibrillation (>7 days).…”

Section: See Page 327 For the Article To Which This Editorial Refersmentioning

confidence: 99%

Cardioversion of chronic atrial fibrillation?towards a more aggressive approach

Lévy

2000

European Heart Journal

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“…Although AF is not excessively disabling in the short term, some patients are even asymptomatic, the long-term consequences are potentially life threatening with thromboembolism, haemodynamic instability, decreased cardiac performance and increased mortality [4,5]. In the general population, AF heralds mortality rate double that of control subjects, in part secondary to the substantial risk of ischaemic stroke [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Duration of warfarin sodium therapy prior to electrical cardioversion of atrial fibrillation

Ryman

Frick

Frykman

et al. 2003

Journal of Internal Medicine

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Objectives. To evaluate the duration of anticoagulation treatment with warfarin sodium before elective DC-cardioversion and to identify clinical variables predicting short-term versus long-term waiting times. Design. Retrospective. Subjects. Patients with a known start date for warfarin sodium, a known duration of atrial fibrillation (AF) and who underwent DC-cardioversion were included. Main outcome measures. Duration of treatment with warfarin sodium prior to DC-cardioversion. Methods. The hospital records of 288 consecutive patients with AF scheduled for elective cardioversion at two hospitals in Stockholm were reviewed. Only patients with a known start date for warfarin sodium and known duration of AF were included in the study.Results. The median age was 70 (26-85) years and the duration of AF at time of cardioversion were 18 weeks (5-273) weeks. The median treatment duration prior to cardioversion with warfarin sodium was 12 weeks. Sinus rhythm was established in 224 (78%) patients of which 90 (40%) remained in sinus rhythm 1 month after cardioversion. In multivariate analysis, the only independent predictor of short waiting times for cardioversion (8 vs. 15 weeks) was if a cardiologist instituted the treatment with warfarin sodium (P < 0.001, 95% CI 5.0-9.0). Conclusion. The average waiting time from start of warfarin sodium treatment to elective cardioversion exceeds by far the recommended 3-4 weeks on therapeutic international normalized ratio (INR). In order to minimize the time period until cardioversion significant changes in the out-of-hospital care logistics has to be undertaken.

show abstract

Atrial fibrillation: current knowledge and recommendations for management*1

Cited by 276 publications

References 183 publications

Spontaneous termination of ventricular fibrillation

Spontaneous termination of ventricular fibrillation

Cardioversion of chronic atrial fibrillation?towards a more aggressive approach

Duration of warfarin sodium therapy prior to electrical cardioversion of atrial fibrillation

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