Atrial Fibrillation at Mid-Term After Bioprosthetic Aortic Valve Replacement

Tosello, F.; Florens, Emmanuelle; Caruba, Thibault; Lebeller, Christine; Mimoun, Léa; Milan, Alberto; Fabiani, Jean‐Noël; Boutouyrie, Pierre; Menasché, Philippe; Lillo‐Lelouet, Agnès

doi:10.1253/circj.cj-14-0684

Cited by 12 publications

(11 citation statements)

References 52 publications

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“…The mean age varied from 56 to 68 years. Fourteen studies [9, 11, 13, 14, 16, 18, 24-31] were from North America (the US and Canada), six studies [15, 32-36] were from Europe, two studies [10, 12] were from Oceania, and two studies [19, 37] were from Asia. Sixteen studies reported the BMI as a categorical variable, eight studies reported the BMI as a continuous variable, and two articles reported the BMI as both a categorical and continuous variable.…”

Section: Resultsmentioning

confidence: 99%

“…We further performed a subgroup analysis by type of cardiac operation. Seventeen articles [13-16, 18, 24, 25, 28, 29, 34, 35, 39, 42] reported the association in coronary artery bypass graft (CABG), two articles [19, 36] reported the association in valve surgery, and seven articles [9-13, 30, 31] reported the association in combined types of cardiac surgery. The summary RRs for a 5-unit increment in BMI in the CABG group, valve surgery group, and combined cardiac surgery group were 1.216 (95% CI: 1.21-1.219, I 2 =80%), 1.34 (95% CI: 0.81-2.22, I 2 =84%), and 1.13 (95% CI: 1.06-1.20, I 2 =79%), respectively (Table 2).…”

Section: Resultsmentioning

confidence: 99%

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Dose-response relationship among body mass index, abdominal adiposity and atrial fibrillation in patients undergoing cardiac surgery: a meta-analysis of 30 prospective studies

liu

Mei²,

et al. 2020

Preprint

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Background: Whether being overweight increases the risk of postoperative atrial fibrillation (POAF) is unclear, and whether adiposity independently contributes to POAF has not been comprehensively studied. Thus, we conducted a meta-analysis to clarify the strength and shape of the exposure-effect relationship between adiposity and POAF. Methods: The PubMed, Cochrane Library, and EMBASE databases were searched for prospective studies (RCTs, cohort studies, and nest-case control studies) reporting data regarding the relationship between adiposity and the risk of POAF. Results: Thirty publications involving 139,302 patients were included. Analysis of categorical variables showed that obesity (RR: 1.39, P<0.001), but not being underweight (RR: 1.44, P=0.13) or being overweight (RR: 1.03, P=0.48), was associated with an increased risk of POAF. In the exposure-effect analysis, the summary RR for a 5-unit increment in body mass index (BMI) was 1.09 (P<0.001) for the risk of POAF. There was a significant linear relationship between BMI and POAF (Pnonlinearity=0.91); the curve was flat and began to rise steeply at a BMI of approximately 30. Notably, BMI levels below 30 (overweight) were not associated with a higher risk of POAF. In the subgroup analysis of surgery types, the pooled RR values for a BMI increase of 5 for coronary artery bypass graft and valve surgery were 1.21 (P<0.01) and 1.34 (P=0.25), respectively, suggesting that a potential difference in the association exists by surgery type. Additionally, waist obesity was associated with the risk of POAF (RR: 1.55, P<0.001). Conclusion: Based on the current evidence, our findings show that adiposity was independently associated with an increased risk of POAF, while being underweight or overweight might not significantly increase the POAF risk. The magnitude of the effect of obesity on AF in patients undergoing valve surgery might be small, and this finding needs to be further confirmed.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Dose-response relationship among body mass index, abdominal adiposity and atrial fibrillation in patients undergoing cardiac surgery: a meta-analysis of 30 prospective studies

liu

Mei²,

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…The mean age varied from 56 to 68 years. Fourteen studies [9,11,13,14,16,18,[25][26][27][28][29][30][31][32] were from North America (the US and Canada), six studies [15,[33][34][35][36][37] were from Europe, two studies [10,12] were from Oceania, and two studies [19,38] were from Asia. Sixteen studies reported the BMI as a categorical variable, eight studies reported the BMI as a continuous variable, and two articles reported the BMI as both a categorical and continuous variable.…”

Section: Study Selectionmentioning

confidence: 99%

“…We further performed a subgroup analysis by type of cardiac operation. Seventeen articles [13-16, 18, 25, 26, 29, 30, 35, 36, 40, 43] reported the association in coronary artery bypass graft (CABG), two articles [19,37] reported the association in valve surgery, and seven articles [9-13, 31, 32] reported the association in combined types of cardiac surgery. The summary RRs for a 5-unit increment in BMI in the CABG group, valve surgery group, and combined cardiac surgery group were 1.216 (95% CI: 1.21-1.219, I 2 = 80%), 1.34 (95% CI: 0.81-2.22, I 2 = 84%), and 1.13 (95% CI: 1.06-1.20, I 2 = 79%), respectively (Table 2).…”

Section: Dose-response Analysis Of the Effect Of Bmi On Poafmentioning

confidence: 99%

Dose-Response Relationship Among Body Mass Index, Abdominal Adiposity and Atrial Fibrillation in Patients Undergoing Cardiac Surgery: A Meta-Analysis of 30 Prospective Studies

Liu¹,

Mei

Xie

et al. 2020

Preprint

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Background: Whether being overweight increases the risk of postoperative atrial fibrillation (POAF) is unclear, and whether adiposity independently contributes to POAF has not been comprehensively studied. Thus, we conducted a meta-analysis to clarify the strength and shape of the exposure-effect relationship between adiposity and POAF.Methods: The PubMed, Cochrane Library, and EMBASE databases were searched for prospective studies (RCTs, cohort studies, and nest-case control studies) reporting data regarding the relationship between adiposity and the risk of POAF.Results: Thirty publications involving 139,302 patients were included. Analysis of categorical variables showed that obesity (RR: 1.39, P<0.001), but not being underweight (RR: 1.44, P=0.13) or being overweight (RR: 1.03, P=0.48), was associated with an increased risk of POAF. In the exposure-effect analysis, the summary RR for a 5-unit increment in body mass index (BMI) was 1.09 (P<0.001) for the risk of POAF. There was a significant linear relationship between BMI and POAF (Pnonlinearity=0.91); the curve was flat and began to rise steeply at a BMI of approximately 30. Notably, BMI levels below 30 (overweight) were not associated with a higher risk of POAF. In the subgroup analysis of surgery types, the pooled RR values for a BMI increase of 5 for coronary artery bypass graft and valve surgery were 1.21 (P<0.01) and 1.34 (P=0.25), respectively, suggesting that a potential difference in the association exists by surgery type. Additionally, waist obesity was associated with the risk of POAF (RR: 1.55, P<0.001).Conclusion: Based on the current evidence, our findings show that adiposity was independently associated with an increased risk of POAF, while being underweight or overweight might not significantly increase the POAF risk. The magnitude of the effect of obesity on AF in patients undergoing valve surgery might be small, and this finding needs to be further confirmed.

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“…Furthermore, quality of life was found to be negatively affected, 6 and POAF is believed to act as a precursor for atrial fibrillation (AF) from a long‐term perspective 7,8 . Apparently, POAF is not only limited to impact on the days after surgery but can also occur in mid‐term period after surgery (<3 months) 9,10 …”

Section: Introductionmentioning

confidence: 99%