ATR-FTIR spectroscopy as the future of diagnostics: a systematic review of the approach using bio-fluids

Naseer, K.A.; Ali, Salmann; Qazi, Javaria

doi:10.1080/05704928.2020.1738453

Cited by 56 publications

(40 citation statements)

References 43 publications

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“…The correlation between ACPA and the wave number characteristic for lipids and cholesterol suggests that it may also be associated with lipid lev els that may be dependent on inflammation levels. Furthermore, the characteristic bands for ACPA were 1340-1345 cm −1 , associated with the amide III of proteins, 1197-1198 cm −1 , associated www.nature.com/scientificreports/ with carbohydrates and creatinine, and 829 cm −1 , associated with the aromatic C-H band 50 . The obtained results suggest that the presence of ACPA may affect the protein profile in sera samples, which can be explained by conformation changes and glycosylation of the autoantibodies.…”

Section: Discussionmentioning

confidence: 99%

Correlations between autoantibodies and the ATR-FTIR spectra of sera from rheumatoid arthritis patients

Durlik-Popińska

Żarnowiec

Konieczna-Kwinkowska³

et al. 2021

Sci Rep

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Rheumatoid arthritis (RA) is one of the most common autoimmune diseases worldwide. Due to high heterogeneity in disease manifestation, accurate and fast diagnosis of RA is difficult. This study analyzed the potential relationship between the infrared (IR) spectra obtained by attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and the presence of autoantibodies and antibodies against urease in sera. Additionally, the wave number of the IR spectrum that enabled the best differentiation between patients and healthy blood donors was investigated. Using a mathematical model involving principal component analysis and discriminant analysis, it was shown that the presence of anti-citrullinated protein antibody, rheumatoid factor, anti-neutrophil cytoplasmic antibodies, and anti-nuclear antibodies correlated significantly with the wave numbers in the IR spectra of the tested sera. The most interesting findings derived from determination of the best predictors for distinguishing RA. Characteristic features included an increased reaction with urease mimicking peptides and a correspondence with particular nucleic acid bands. Taken together, the results demonstrated the potential application of ATR-FTIR in the study of RA and identified potential novel markers of the disease.

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Section: Discussionmentioning

confidence: 99%

Correlations between autoantibodies and the ATR-FTIR spectra of sera from rheumatoid arthritis patients

Durlik-Popińska

Żarnowiec

Konieczna-Kwinkowska³

et al. 2021

Sci Rep

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Section: A Brief Background In Vibrational Spectroscopymentioning

confidence: 99%

“…Near and mid infrared and Raman spectroscopy are part of a family of techniques that belong to vibrational spectroscopy [18][19][20][21][22][23]. These techniques have been applied to measure and quantify a wide range of chemical compounds, biochemical and functional properties in different food matrices, as well as in agricultural commodities, including fruits and vegetables [18][19][20][21][22][23]. The vibrational spectrum behaves as the so called "fingerprint", and has the potential to quantify, qualify, characterise and elucidate the intrinsic characteristic of any biological samples [18][19][20][21][22][23].…”

Section: A Brief Background In Vibrational Spectroscopymentioning

confidence: 99%

An Overview of the Successful Application of Vibrational Spectroscopy Techniques to Quantify Nutraceuticals in Fruits and Plants

Cozzolino

2022

Foods

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Vibrational spectroscopy techniques are the most used techniques in the routine analysis of foods. This technique is widely utilised to measure and monitor the proximate chemical composition (e.g., protein, dry matter, fat and fibre) in an array of agricultural commodities, food ingredients and products. Developments in optics, instrumentation and hardware concomitantly with data analytics, have allowed for the progress in novel applications of these technologies in the field of nutraceutical and bio compound analysis. In recent years, several studies have demonstrated the capability of vibrational spectroscopy to evaluate and/or measure these nutraceuticals in a broad selection of fruit and plants as alternative to classical analytical approaches. This article highlights, as well as discusses, the challenges and opportunities that define the successful application of vibrational spectroscopy techniques, and the advantages that these techniques have to offer to evaluate and quantify nutraceuticals in fruits and plants.

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“…(Other disorders) 1 SERS Saliva. Sjögren's syndrome (SjS) 2020 [Moisoiu 2020] 96.5% 2 ATR-IR Periodontal Diseases 2020 [Beyer-Hans et al 2020 ] _ 3 ATR-FTIR Bio fluids including saliva; Review, clinical applications 2020 [Naseer et al 2020 ] _ 4 Raman Amyotrophic Lateral Sclerosis (ALS) diagnosis 2020 [Carlomagno et al 2020 ] _ 5 SERS Periodontitis, Sialic Acid (SA) 2019 [Hernández-Cedillo et al 2019 ] 69.6% 6 SERS To evaluate the activity of urease in saliva. Dental caries; helicobacter pylori infection 2019 [Hu et al 2019 ] L.O.D: 2.35 μg/ml 7 SERS biomarkers of bronchial inflammation in the saliva of children with asthma 2019 [Zamora-Mendoza et al 2019 ] 85% 8 ATR-FTIR Chronic kidney disease 2019 [Rodrigues et al 2019a , b ] 92.8% 9 FTIR Burning Mouth Syndrome 2019 [Rodrigues et al 2019a , b ] _ 10 FTIR Neonatal sepsis using saliva 2019 [Yunanto et al 2019 ] _ 11 ATR-FTIR Multiple dental caries 2018 [Seredin et al 2018 ] _ 12 Plasmonics Hepatitis B 2017 [Riedel et al 2017 ] _ 13 IR …”

Section: Summary and Future Prospectsmentioning

confidence: 99%

Photonics of human saliva: potential optical methods for the screening of abnormal health conditions and infections

Lukose

Mithun

et al. 2021

Biophys Rev

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Human saliva can be treated as a pool of biological markers able to reflect on the state of personal health. Recent years have witnessed an increase in the use of optical devices for the analysis of body fluids. Several groups have carried out studies investigating the potential of saliva as a non-invasive and reliable clinical specimen for use in medical diagnostics. This brief review aims to highlight the optical technologies, mainly surface plasmon resonance (SPR), Raman, and Fourier transform infrared (FTIR) spectroscopy, which are being used for the probing of saliva for diverse biomedical applications. Advances in bio photonics offer the promise of unambiguous, objective and fast detection of abnormal health conditions and viral infections (such as COVID-19) from the analysis of saliva.

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ATR-FTIR spectroscopy as the future of diagnostics: a systematic review of the approach using bio-fluids

Cited by 56 publications

References 43 publications

Correlations between autoantibodies and the ATR-FTIR spectra of sera from rheumatoid arthritis patients

Correlations between autoantibodies and the ATR-FTIR spectra of sera from rheumatoid arthritis patients

An Overview of the Successful Application of Vibrational Spectroscopy Techniques to Quantify Nutraceuticals in Fruits and Plants

Photonics of human saliva: potential optical methods for the screening of abnormal health conditions and infections

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