2022
DOI: 10.1016/j.ijpx.2022.100140
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Atorvastatin-loaded emulsomes foam as a topical antifungal formulation

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Cited by 3 publications
(4 citation statements)
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References 78 publications
(92 reference statements)
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“…20,23 However, because of the many side effects associated with systemic statins and the drug-drug interactions between systemic statins and antifungals, it was appealing to investigate the antifungal efficacy of topical statins. Topical treatment requires the right vehicle to be delivered efficiently; the ones found to be effective were the emulgels containing the statin of choice 31 and statin emulsomes loaded into a foam system. 36 Topical statins were found to be efficient against oral and vaginal candidiasis, skin Candida albicans, Sporotrichosis, and Malassezia spp.…”
Section: Discussionmentioning
confidence: 99%
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“…20,23 However, because of the many side effects associated with systemic statins and the drug-drug interactions between systemic statins and antifungals, it was appealing to investigate the antifungal efficacy of topical statins. Topical treatment requires the right vehicle to be delivered efficiently; the ones found to be effective were the emulgels containing the statin of choice 31 and statin emulsomes loaded into a foam system. 36 Topical statins were found to be efficient against oral and vaginal candidiasis, skin Candida albicans, Sporotrichosis, and Malassezia spp.…”
Section: Discussionmentioning
confidence: 99%
“…Another study, conducted by Eita et al 31 in 2022, studied the treatment of rats infected with Candida albicans using a modified form of the emulgel: the foam vehicle. Foams have recently been gaining popularity as the vehicles of preference in skin therapy.…”
Section: Topical Statinsmentioning
confidence: 99%
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“…The concept of repurposing involves exploring alternative therapeutic applications for drugs that have already been approved for different uses. In other words, it involves finding new ways to utilize previously authorized medications [ 16 , 17 ].…”
Section: Introductionmentioning
confidence: 99%