2016
DOI: 10.1024/0040-5930/a000819
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Atopische Dermatitis und Malassezia spp.

Abstract: Zusammenfassung. Die atopische Dermatitis (AD) ist eine chronisch entzündliche Hauterkrankung. Dabei findet man recht häufig eine für die Erkrankung nahezu pathognomonische IgE-vermittelte Sensibilisierung auf Hefepilze der Gattung Malassezia spp. Die pathogenetische Rolle von Malassezia spp. bei AD ist noch nicht völlig geklärt. Möglicherweise spielen auto-reaktive T Lymphozyten die zwischen Malassezia spp. Allergenen und homologen Proteinen in der Haut von AD Patienten kreuzeagieren eine besondere Rolle. Ein… Show more

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“…Several randomized, placebo‐controlled trials have investigated the effect of systemic antifungal treatment on AD. Some have shown a significant difference in reduction of AD severity in patients treated with oral ketoconazole vs. placebo or oral itraconazole vs. placebo 898,899 . However, the relevance of these results to routine clinical practice remains to be demonstrated.…”
Section: B08 – Microbial Allergens /Antigensmentioning
confidence: 99%
“…Several randomized, placebo‐controlled trials have investigated the effect of systemic antifungal treatment on AD. Some have shown a significant difference in reduction of AD severity in patients treated with oral ketoconazole vs. placebo or oral itraconazole vs. placebo 898,899 . However, the relevance of these results to routine clinical practice remains to be demonstrated.…”
Section: B08 – Microbial Allergens /Antigensmentioning
confidence: 99%