Atopic Dermatitis: The (Wet) Wrap: Up

Nicol, Noreen Heer

doi:10.2307/3425966

Cited by 11 publications

(15 citation statements)

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“…Twenty-one articles provided expert opinions or were reviews (1,4,5,7,8,(35)(36)(37)(38)(39)(40)(41)(42)(43)(44)(45)(46)(47)(48)(49)(50). Table I provides an overview of the quality assessment of the 8 human comparative studies.…”

Section: Resultsmentioning

confidence: 99%

The Role of Wet Wrap Therapy in Skin Disorders – A Literature Review

Andersen¹,

Thyssen²,

Maibach³

2015

Acta Derm Venerol

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Wet wrap therapy, based on skin application of a double layer of tubular bandages or gauze with a moist first inner layer and a dry second outer layer, is utilized to treat various pruritic conditions, in particular severe and refractory atopic dermatitis. This review, by literature search, evaluates current knowledge about wet wrap therapy. Wet wrap therapy superimposed topical corticosteroids appears more efficient than emollients only, at least for short-time treatments. Despite higher efficacy, there is a tendency towards more frequent infections when topical corticosteroids are covered with wet wrap bandages compared to emollients only. While temporary suppression of hypothalamic-pituitary-adrenocortical-axis was seen due to systemic bioactivity of corticosteroids, no long-term observation studies on putative adverse effects were identified. One hypothesis suggests that wet wrap therapy may trigger increased lamellar body secretion resulting in recovery of the damaged intercellular lipid laminar structure. Otherwise, little investigation on mechanisms exists.

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Section: Resultsmentioning

confidence: 99%

The Role of Wet Wrap Therapy in Skin Disorders – A Literature Review

Andersen¹,

Thyssen²,

Maibach³

2015

Acta Derm Venerol

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“…88 Investigators have shown that wet wraps with steroids improve various aspects of AD, including pruritus and/or excoriations. Side effects reported include chills, folliculitis, and impetigo, with a rarer incidence of cutaneous pseudomonas infection, herpetic infections, and adrenal suppression.…”

Section: Topical Therapiesmentioning

confidence: 99%

Management of Itch in Atopic Dermatitis

Hong¹,

Buddenkotte²,

Berger³

et al. 2011

Seminars in Cutaneous Medicine and Surgery

127

105

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Atopic dermatitis is a common, pruritic, inflammatory skin disorder. Chronic, localized, or even generalized pruritus is the diagnostic hallmark of atopic dermatitis, and its management remains a challenge for physicians. The threshold for itch and alloknesis is markedly reduced in these patients, and infections can promote exacerbation and thereby increase the itch. Modern management consists of anti-inflammatory, occasionally antiseptic, as well as antipruritic therapies to address the epidermal barrier as well as immunomodulation or infection. Mild forms of atopic dermatitis may be controlled with topical therapies, but moderate-to-severe forms often require a combination of systemic treatments consisting of antipruritic and immunosuppressive drugs, phototherapy, and topical compounds. In addition, patient education and a therapeutic regimen to help the patient cope with the itch and eczema are important adjuvant strategies for optimized long-term management. This review highlights various topical, systemic, and complementary and alternative therapies, as well as provide a therapeutic ladder for optimized long-term control of itch in atopic dermatitis.

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“…Islak sargı uygulaması 1987 yılında tanımlanan, orta ve ağır AD'li hastaların tedavisinde önerilebilecek, topikal uygulanan ajanın emilimini artırmayı amaçlayan etkili bir tedavi yöntemidir 93 . Uygulamada deri banyo yoluyla ıslatılır.…”

Section: Islak Sargı Uygulamasıunclassified