Atopic Dermatitis and Malassezia Species: A Study of Antigenic Components of Malassezia Species for Immunoglobulin E of Patients with Atopic Dermatitis

Kanbe, Toshio; Koyama, Tomoki

doi:10.3314/jjmm.44.71

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…Another study indicates that a glycoprotein, Malg46b of M globosa, is dominantly expressed in this fungus and is a possible major antigen for IgE antibodies in patients with AD. 131 Recent work has also indicated that AD is linked to a family of cytokine genes (IL-3, IL-4, IL-5, IL-13, and granulocyte-macrophage colony stimulating factor) located on chromosome 5q31-33. 132,133 Because yeasts appear to be involved in only a subset of patients with AD, there has been little research into their role in this disease, compared with work done on the conditions described above.…”

Section: Admentioning

confidence: 98%

Skin diseases associated with Malassezia species

Gupta

Batra

Bluhm

et al. 2004

Journal of the American Academy of Dermatology

434

359

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Section: Admentioning

confidence: 98%

Skin diseases associated with Malassezia species

Gupta

Batra

Bluhm

et al. 2004

Journal of the American Academy of Dermatology

434

359

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“…The 17-kDa component (i.e., MGL_1304) has a high histamine-releasing property and it is also an important antigen for patients with atopic dermatitis and cholinergic urticaria. In contrast, the glycoprotein Malg46b component of M. globosa acts as a major antigen for IgE antibodies in patients with atopic dermatitis (9). It can be speculated that the protein components of Malassezia may act as haptens under specific environmental conditions of stimulation.…”

Section: Discussionmentioning

confidence: 99%

Malassezia infection associated with chronic spontaneous urticaria without angioedema: a report on five cases

Zawar¹,

Pawar²,

Kumavat³

2018

Acta Dermatovenerologica Alpina Pannonica Et Adriatica

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Introduction: Chronic spontaneous urticaria (CSU) is a challenging condition to treat and it significantly affects quality of life. Bacterial, viral, parasitic, and fungal infections have been associated with triggering and/or perpetuating urticaria in certain individuals. There is a paucity of literature on CSU associated with Malassezia infection. Methods and results: We present a case series of five patients with CSU without angioedema in whom we observed temporal association of Malassezia infection with CSU. The presence of Malassezia was confirmed by clinical examination, Wood's lamp, and KOH examination. The patients with CSU experienced improvement after specific antifungal therapy. Conclusion: Malassezia infection may be associated with recurrent and chronic urticaria in a certain group of susceptible patients and thus specific targeted therapy against it might result in complete remission of urticaria along with clearing of the infection.

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Atopic Dermatitis and Malassezia Species: A Study of Antigenic Components of Malassezia Species for Immunoglobulin E of Patients with Atopic Dermatitis

Cited by 2 publications

References 7 publications

Skin diseases associated with Malassezia species

Skin diseases associated with Malassezia species

Malassezia infection associated with chronic spontaneous urticaria without angioedema: a report on five cases

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