Atopic Dermatitis

Contact allergy in children with atopic dermatitis: a systematic review

“…Atopic dermatitis (AD) is the most common inflammatory skin disease in childhood, affecting 15–30% of children . Although the pathogenesis of AD is complex and multifactorial, the disease has a common phenotypic expression, characterized by dry and itchy skin with chronic or recurrent episodes of dermatitis at typical anatomical sites . AD was traditionally considered an immune‐mediated condition, driven primarily by T helper (Th)2 cells, and individuals with AD were considered less likely to have allergic contact dermatitis (ACD) owing to suppressed Th1‐mediated cellular immunity .…”

Clinical and histopathological findings of ‘psoriatic neurodermatitis’ and of typical lichen simplex chronicus

“…Lichen simplex chronicus is also known as circumscribed neurodermatitis 7 . The noun ‘neurodermatitis’, particularly with the adjectives ‘generalized’ or ‘disseminated’, is also used for atopic dermatitis by some authors 12 . So, one may suggest that the so‐called PN might be ‘atopic dermatitis’, since it could cause many and generalized plaques.…”

Is topical antimycotic treatment useful as adjuvant therapy for flexural atopic dermatitis: randomized, double‐blind, controlled trial using one side of the elbow or knee as a control

“…Atopic dermatitis (AD) is a chronic, relapsing, itchy, inflammatory skin condition usually starting from childhood 1 . Only around one‐third of AD patients suffer from skin problems alone according to a Singapore study; 2 the remaining patients often also suffer from other atopic conditions, such as rhinitis, asthma, and hay fever.…”

“…Certain factors are known to cause exacerbation in AD, e.g. soap, detergent, dry skin, staphylococcal colonization, and herpes infection 3 . Other factors are suspected, but not proven, e.g.…”

“…Although AD patients often have elevated serum IgE to a wide range of allergens, the significance of this observation for the pathogenesis of AD has remained unclear 10 . Therefore, the value of using Malassezia ‐specific IgE prevalence as pathophysiologic evidence in AD also remains unclear.…”