Atopic Characteristics of Adult Patients With Eosinophilic Esophagitis

Roy-Ghanta, Sumita; LaRosa, David F.; Katzka, David A.

doi:10.1016/j.cgh.2007.12.045

Cited by 188 publications

(147 citation statements)

References 33 publications

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“…Less common complaints include heartburn, regurgitation and chest pain, which may on occasion mislead towards GERD (9,10). Furthermore, as this condition has an immune and allergic background, patients frequently exhibit comorbid atopy, asthma, and food allergies (11)(12)(13).…”

Section: Introductionmentioning

confidence: 99%

Impaired esophageal motor function in eosinophilic esophagitis

Santander¹,

Chavarría²,

Becerro-González³

et al. 2015

Rev Esp Enferm Dig

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Eosinophilic esophagitis is a chronic immunoallergic inflammatory disease of the esophagus that represents a major cause of digestive morbidity among the pediatric and young adult populations. Despite the fact that key symptoms in adults include dysphagia and food impaction, many patients lack structural changes in the esophagus to account for their complaints, which suggests the presence of underlying motor disorders and esophageal distensibility impairment. In the last few years the esophageal motility of these patients has been studied using various approaches, most particularly high-resolution manometry, ambulatory manometry, and impedance planimetry. This review focuses on the most relevant findings and scientific evidence regarding esophageal motor disorders in eosinophilic esophagitis.

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Section: Introductionmentioning

confidence: 99%

Impaired esophageal motor function in eosinophilic esophagitis

Santander¹,

Chavarría²,

Becerro-González³

et al. 2015

Rev Esp Enferm Dig

View full text Add to dashboard Cite

show abstract

“…For example, adult patients seem to present a higher proportion of IgE-mediated positive allergy results than children in whom sensitization to both indoor and outdoor antigens have been documented [20,25]. Both types of antigens have been demonstrated to cause experimental EoE [26].…”

Section: Allergy Study Results In Eoe Patientsmentioning

confidence: 99%

“…The majority of EoE patients present a family and/or personal allergic background, commonly presenting with asthma, rhinitis, conjunctivitis and eczema with variable frequency [1]. Moreover, food and aeroallergen sensitization have been commonly described in patients of all ages [12,20]. However, even though food-specific IgE or skin prick test (SPT) results were positive in over 80% of adult patients [21], elimination of foods that gave positive results failed to achieve disease remission [22].…”

Section: Allergy Study Results In Eoe Patientsmentioning

confidence: 99%

Adult versus pediatric eosinophilic esophagitis: important differences and similarities for the clinician to understand

Lucendo

Sánchez-Cazalilla

2012

Expert Review of Clinical Immunology

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“…It is characterized histologically by eosinophilpredominant inflammation of the esophagus [2]. The exact pathogenesis of the disease is unknown but it is closely associated with atopic disease such as asthma, allergic rhinitis and eczema [3]. A complex interplay of environmental/food allergen and host immune system in a genetically predisposed individual forms the basis [4,5].…”

Section: Discussionmentioning

confidence: 99%