Atomic Force Microscopy in Detection of Viruses

A New Method of AFM‐Based Nanolithography Using Frequency Enhanced Electrochemical Pressure Solution Etching

“…The wear mechanism studied herein is therefore of a different nature to traditional tribochemistry, shear induced processes as indeed 1) more shear leads less wear and 2) the power law observed is characteristic of FEEPS induced processes. [ 8 ] Further, the use of intermittent contact mode in etching experiments where little to no shear is present [ 29 ] enables us to rule out any traditional tribochemical wear, bond bridging like mechanism, and confirm the presence of a FEEPS like etching behaviour in our system.…”

“…The use of the AFM in tapping mode (TM) greatly increases the tip longevity as low to no tip wear is recorded. Further, the use of intermittent contact mode in etching experiments where little to no shear is present [ 29 ] enables us to rule out any traditional tribochemical wear, bond bridging like mechanism and confirm the presence of a FEEPS like etching behavior in our system. Additionally, gray‐scale lithography becomes feasible by controlling the time allocated to the tip to dissolve the substrate, simply by varying its velocity across the surface.…”

Addressing the Silent Spread of Monkeypox Disease with Advanced Analytical Tools

“…The previous research on the poxviridae family by AFM methods [ 155 ] demonstrate the considerable ability of AFM to image and extract the morphological species of monkeypox. In general, to study the poxviridae family, especially MPXV, AFM can provide following information: i) determine the properties of affected cells by monkeypox; ii) explore the interplay between MPXV and host cell; iii) investigate the mechanism of MPXV to cross the cellular membrane as well as transport the monkeypox genome into the host cell and finally iv) its reproduction and characterization of the nucleic acids to comprehend the mechanism of condensing and packaging inside capsids.…”