“…They are essential for cellular ion and pH homeostasis and play significant roles in diverse cellular processes (Bassil, Coku, & Blumwald, ; Chanroj et al, ; Pardo, Cubero, Leidi, & Quintero, ; Qiu, ; Reguera, Bassil, & Blumwald, ). AtNHX5 and AtNHX6, which share high sequence similarity (78.7%), are endosomal NHX antiporters that are localized in the Golgi, transâGolgi network (TGN), and prevacuolar compartment (PVC) (Pardo et al, ; Qiu, ; Qiu, ; Reguera et al, ; Yokoi et al, ). Studies showed that nhx5 nhx6 double mutant was defective in development, having smaller rosettes and shorter seedlings (Bassil et al, ; Wang, Wu, Liu, & Qiu, ; Wu, Ebine, Ueda, & Qiu, ).…”