Atmospheric pressure gas chromatography–time-of-flight-mass spectrometry (APGC–ToF-MS) for the determination of regulated and emerging contaminants in aqueous samples after stir bar sorptive extraction (SBSE)

Pintado-Herrera, Marina G.; González-Mazo, Eduardo; Lara-Martín, Pablo A.

doi:10.1016/j.aca.2014.05.030

Cited by 110 publications

(41 citation statements)

References 37 publications

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“…As a consequence, SPME is becoming more widely used, owing to its ability for quick screening of targeted analytes and its simplicity [32], with existing applications in the field of UV filters. However, the more sensitive applications require the use of additional reagents for the derivatization of the analytes [33] or the measurements were performed by MS/MS [34].…”

Section: Introductionmentioning

confidence: 99%

Fast determination of octinoxate and oxybenzone uv filters in swimming pool waters by gas chromatography/mass spectrometry after solid‐phase microextraction

Yilmazcan

Kanakaki

İzgi

et al. 2015

J of Separation Science

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A fast gas chromatography/mass spectrometry method was developed and validated for the analysis of the potential endocrine disrupters octinoxate and oxybenzone in swimming pool water samples based on the solvent-free solid-phase microextraction technique. The low-pressure gas chromatography/mass spectrometry method used for the fast identification of UV filter substances was compared to a conventional method in terms of sensitivity and speed. The fast method proposed resulted in 2 min runs, leading to an eightfold decrease in the total analysis time and a sevenfold improvement in detection limits. The main parameters affecting the solid-phase microextraction process were also studied in detail and the optimized conditions were as follows: fiber coating, polyacrylate; extraction mode, direct immersion; extraction temperature, 25°C; sample volume, 5 mL; extraction time 45 min; pH 6.5. Under the optimized conditions, a linear response was obtained in the concentration range of 0.5-25 μg/L with correlation coefficients in the range 0.990-0.999. The limits of detection were 0.17-0.29 μg/L, and the recoveries were 80-83%. Combined method uncertainty was assessed and found to be less than 7% for both analytes for concentrations equal to or higher than 5 μg/L. Pool water samples were analyzed to demonstrate the applicability of the proposed method. Neither octinoxate nor oxybenzone were detected in the swimming pool water samples at concentrations above the respective limits of detection.

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Section: Introductionmentioning

confidence: 99%

Fast determination of octinoxate and oxybenzone uv filters in swimming pool waters by gas chromatography/mass spectrometry after solid‐phase microextraction

Yilmazcan

Kanakaki

İzgi

et al. 2015

J of Separation Science

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“…atmospheric pressure chemical ionisation (APCI), facilitating the detection of the molecular ion (or protonated molecule) which in turn eases the derivation of possible molecular formulae. The potential of GC‐(APCI)TOF‐MS has recently been demonstrated in other fields, such as pesticide residue or water analysis . To our knowledge, its application to the analysis of migrants from plastic FCMs has been rather limited.…”

Section: Introductionmentioning

confidence: 99%

Identification of substances migrating from plastic baby bottles using a combination of low‐resolution and high‐resolution mass spectrometric analysers coupled to gas and liquid chromatography

et al. 2015

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This work presents a strategy for elucidation of unknown migrants from plastic food contact materials (baby bottles) using a combination of analytical techniques in an untargeted approach. First, gas chromatography (GC) coupled to mass spectrometry (MS) in electron ionisation mode was used to identify migrants through spectral library matching. When no acceptable match was obtained, a second analysis by GC‐(electron ionisation) high resolution mass spectrometry time of flight (TOF) was applied to obtain accurate mass fragmentation spectra and isotopic patterns. Databases were then searched to find a possible elemental composition for the unknown compounds. Finally, a GC hybrid quadrupole‐TOF‐MS with an atmospheric pressure chemical ionisation source was used to obtain the molecular ion or the protonated molecule. Accurate mass data also provided additional information on the fragmentation behaviour as two acquisition functions with different collision energies were available (MSE approach). In the low‐energy function, limited fragmentation took place, whereas for the high‐energy function, fragmentation was enhanced. For less volatile unknowns, ultra‐high pressure liquid chromatography‐quadrupole‐TOF‐MS was additionally applied. Using a home‐made database containing common migrating compounds and plastic additives, tentative identification was made for several positive findings based on accurate mass of the (de)protonated molecule, product ion fragments and characteristic isotopic ions. Six illustrative examples are shown to demonstrate the modus operandi and the difficulties encountered during identification. The combination of these techniques was proven to be a powerful tool for the elucidation of unknown migrating compounds from plastic baby bottles. Copyright © 2015 John Wiley & Sons, Ltd.

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“…8 Prior to chromatographic analysis, a sample preparation technique is used to remove or reduce potential interferents from the matrix and also to concentrate the analytes. Different sample preparation techniques have been employed for the determination of ultraviolet filters in water samples, such as ultrasound-assisted e m u l s i fi c a t i o n m i c r o ex t r a c t i o n ( U S A E M E ) , 7 dispersive liquid-liquid microextraction (DLLME), [9][10][11] stir-bar sorptive-extraction (SBSE), 12 stir-bar sorptive-dispersive microextraction (SBSDµE), 13,14 bar adsorptive microextraction (BAµE) 3 and solid-phase microextraction (SPME). [15][16][17] In this study, cork fiber was proposed for use in the determination of two ultraviolet filters in river water samples, 3-(4-methylbenzylidene)camphor and 2-ethylhexyl 4-(dimethylamino)benzoate, which are from different Exploiting Cork as Biosorbent Extraction Phase for Solid-Phase Microextraction J. Braz.…”

Section: Introductionmentioning

confidence: 99%

Exploiting Cork as Biosorbent Extraction Phase for Solid-Phase Microextraction to Determine 3-(4-Methylbenzylidene)camphor and 2-Ethylhexyl 4-(Dimethylamino)benzoate in River Water by Gas Chromatography-Mass Spectrometry

Silva¹,

Dias²,

Carasek³

2017

J. Braz. Chem. Soc.

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In this study, a method for the determination of 3-(4-methylbenzylidene)camphor (4-MBC) and 2-ethylhexyl 4-(dimethylamino)benzoate (OD-PABA) in river water samples employing cork as the SPME (solid-phase microextraction) fiber was developed. The extraction parameters optimized were pH, ionic strength and extraction time and temperature. For the extraction step, the sample pH was studied in univariate experiments while the extraction time, temperature and ionic strength were evaluated using a central composite design. The optimal extraction conditions were sample pH 4.0, extraction time 70 min, sample temperature 80 °C and sodium chloride concentration 6% (m v , respectively. The linear correlation coefficients were greater than 0.97 for both analytes and the developed method showed recovery values between 67 and 107%. In an evaluation of the fiber-to-fiber reproducibility (fibers produced by different analysts), the relative standard deviation (RSD) was lower than 11% (n = 6).

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Atmospheric pressure gas chromatography–time-of-flight-mass spectrometry (APGC–ToF-MS) for the determination of regulated and emerging contaminants in aqueous samples after stir bar sorptive extraction (SBSE)

Cited by 110 publications

References 37 publications

Fast determination of octinoxate and oxybenzone uv filters in swimming pool waters by gas chromatography/mass spectrometry after solid‐phase microextraction

Fast determination of octinoxate and oxybenzone uv filters in swimming pool waters by gas chromatography/mass spectrometry after solid‐phase microextraction

Identification of substances migrating from plastic baby bottles using a combination of low‐resolution and high‐resolution mass spectrometric analysers coupled to gas and liquid chromatography

Exploiting Cork as Biosorbent Extraction Phase for Solid-Phase Microextraction to Determine 3-(4-Methylbenzylidene)camphor and 2-Ethylhexyl 4-(Dimethylamino)benzoate in River Water by Gas Chromatography-Mass Spectrometry

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