Atherosclerosis in Ruminants

Unusual Lesions of Atherosclerosis in Psittacines

“…In the published cases of atherosclerosis in domestic bird species, spontaneous lesions were often identified with a higher prevalence in older animals and thought to be associated with a decreased dietary intake of saturated fatty acids and hypercholestolemia. 14,15 These lesions rarely cause clinical disease. In dogs, there is evidence of Chlamydophila psittaci within atherosclerotic lesions, proposing similarities between canine disease manifestation and humans and alluding to proposed human models of this disease.…”

Atherosclerosis in ruminants

“…Total liver weights were recorded; core samples of each liver were lyophilized and analyzed for total cholesterol as described previously (Wiggers, Jacobson and Getty, 1971).…”

“…Both analyses were 2 run on a Technicon Auto-Analyzer , cholesterol as suggested by Technicon (1965) and triglycerides by the method of Kessler and Lederer (1966) as 3 modified by Ewan , i.e., silicic acid was used in lieu of zeolite. Total cholesterol in liver extracts was also determined; preparation of liver extracts for analysis has been described previously (Wiggers, Jacobson and Getty, 1971 Plasma magnesium levels were determined by use of an atomic absorption spectrophotometer^; 0.5 ml of plasma was diluted to 50 ml with 17o certified lanthanum chloride^ solution. Magnesium standards made with MgCL^'SH^O were compared to Lab-Trol^ standards.…”

“…The total 6-day fecal collection was pooled and mixed before a sample was withdrawn for cholesterol analysis. The fecal samples were lyophilized and cholesterol was extracted in the same manner described for cholesterol extraction from liver (Wiggers, Jacobson and Getty, 1971 At 0, 0.5, 1, 2, 3, 4, 5 and 6 hours, the incubation mixture was mixed thoroughly and a 10 ral sample withdrawn. After each sampling, the flask was flooded with nitrogen gas and replaced in the continuousaction shaker.…”

Effect of diet and exercise on atherosclerosis in the goat

“…The data for goats were from Experiments 1 and II. The calf data were from research by Wiggers(116). The MC diet created significantly higher plasma cholesterol concentration in both species than did the HGC diet.…”