Atherosclerosis in Ancient Egyptian Mummies

Allam, Adel H.; Thompson, Randall C.; Wann, L. Samüel; Miyamoto, Michael I.; El-Din, Abd El Halim Nur; el-Maksoud, Gomaa Abd; Al-Tohamy, Muhammad; Badr, Ibrahem; Amer, Hamada H.; Sutherland, M. Linda; Sutherland, James D.; Thomas, Gregory S.

doi:10.1016/j.jcmg.2011.02.002

Cited by 130 publications

(77 citation statements)

References 23 publications

(16 reference statements)

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“…In recent studies, this condition has been the subject of investigation in mummified remains. In particular, to assess whether atherosclerosis was a condition dependent on the lifestyle of Egyptian elites or if it was also encountered in ancient populations with different subsistence strategies (Allam et al, 2009(Allam et al, , 2011Thompson et al, 2013). Studies have demonstrated atherosclerosis in other prehistoric and historic mummies, including the chalcolithic Iceman, a mummy from the Joseon dynasty, and a pre-agricultural hunter-gatherer population from the Aleutian Islands (Murphy et al, 2003;Abdelfattah et al, 2013;Kim et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

Paleopathology in the Piraino mummies as illustrated by X-rays

Piombino‐Mascali

Zink

Panzer³

2017

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This paper presents the first radiological investigation of a collection of Sicilian mummies held in a crypt beneath the Mother Church of Piraino, Italy. The chamber contains 26 preserved bodies of religious dignitaries, either conserved vertically in special wall niches or horizontally on wooden shelves. The majority of bodies are clothed, and transportation outside of the crypt was not feasible. Therefore assessment of the remains via paleoradiological methods appeared to be the most convenient approach to investigate this precious ethno-anthropological heritage. Radiological examination of 23 of these mummies yielded information relating to their funerary treatment and some of the pathological alterations associated with the remains. These included osteoarthritis, diffuse idiopathic skeletal hyperostosis, and neoplasms, as well as any trauma present. These analyses provided insights into mortuary behavior and the osteobiographies of these clerical figures.

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Section: Discussionmentioning

confidence: 99%

Paleopathology in the Piraino mummies as illustrated by X-rays

Piombino‐Mascali

Zink

Panzer³

2017

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“…Diameter and blood velocity recordings resumed prior to cuff deflation and continued for 5 min for SFA and 3 min for the BA after deflation. Ultrasound images were continuously recorded at 5 frames·s −1 with Camtasia (TechSmith, Okemos, Mich., USA), and stored as .avi files [5,8]. This procedure was repeated hourly across the sitting intervals.…”

Section: Sfa and Ba Fmdmentioning

confidence: 99%

“…Arterial diameters and blood velocities: Off-line analysis of diameters were performed using automated edgedetection software (Brachial Analyzer, Medical Imaging Applications LLC, Coralville, IA, USA) as previously described [8,9]. This software allows the technician to determine a region of interest where the near and far vessel walls are most clear.…”

Section: Sfa and Ba Fmdmentioning

confidence: 99%

“…Sitting creates a unique anatomical and physiological milieu in the legs including bends in the femoral and popliteal artery, increased viscosity [3], blood pressure [4] and decrease in arterial shear rates [5]. Interestingly in humans, lower extremities exhibit an increased distribution of atherosclerosis as compared to the upper extremities [6][7][8]. There may be various reasons for this disparity.…”

Section: Introductionmentioning

confidence: 99%

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Seven Days Breaking Up Prolonged Sitting Improves Systemic Endothelial Function in Sedentary Men

Park¹,

Yoon²,

Jae³

2017

Exerc Sci

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Introduction: It is unknown if there are limb differences in vascular function during prolonged sitting. Purpose: This study was designed to test whether the effects of prolonged sitting on brachial artery (BA) and the superficial femoral artery (SFA) are similar. Methods: Twelve men (24.2 ± 4 yrs.) participated in a 3 hr prolonged sitting trial (SIT). SFA and BA flow mediated dilation (FMD) and respective flow patterns were measured at baseline, 1 hr, 2 hr and 3 hr.

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“…Evidence from post mortem studies demonstrated the presence of atheromatous lesions in coronary arteries in children (Stary 2000). It is often thought of as a disease associated with a modern sedentary lifestyle and a lipid abundant diet Recently Allam and colleagues (Allam et al 2011) have imaged fifty two ancient Egyptian mummies using multi slice computer tomography and identified atherosclerotic lesions (arterial wall calcification) in 45% of cases with calcification sites located in the aorta, coronary carotid, iliac and femoral arteries as well as in peripheral arteries.…”

Section: Introductionmentioning

confidence: 99%