Asymptomatic viruses detectable in saliva in the first year of life: a narrative review

Goh, Melody; Joy, Charissa; Gillespie, Alanna N.; Soh, Qi Rui; He, Fan; Sung, Valerie

doi:10.1038/s41390-023-02952-0

Cited by 2 publications

(1 citation statement)

References 198 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The first contact and infection of many pathogens occurs during childhood. There is an increased interest in the field of infections among infants and children [ 26 ]. The pathogenic potential in the oral cavity can be increased by local conditions such as poor oral hygiene or advanced caries lesions [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

Molecular Detection of HPV, EBV, HSV-1, HCMV, and H. pylori Pathogens: An Evaluation among Polish Children with Molar Incisor Hypomineralization (MIH)

Tynior,

Świętek,

Hudy

et al. 2024

Pathogens

View full text Add to dashboard Cite

Molar incisor hypomineralization (MIH) is a congenital disorder of the enamel tissue, characterized by a quantitative deficiency. In childhood, infections such as EBV, HSV-1, HCMV, or H. pylori may occur and cause various diseases. This study aimed to investigate the prevalence of HPV, EBV, HSV-1, HCMV, and H. pylori infections in two groups of children: children with molar incisor hypomineralization (MIH) and a control group, using molecular methods. The study group included 47 children aged between 6–13 years who had been diagnosed with MIH. The control group consisted of 42 children. The study found that, in the MIH group, the prevalence of HPV-16 was 6.38%, HPV-18 was 4.26%, EBV was 31.91%, HSV-1 was 4.26%, HCMV was 4.26%, and H. pylori was 12.77%. There were no significant differences in the prevalence of any of tested pathogens between the study and the control group (p > 0.05). However, the study found a higher prevalence of EBV infection in children who had smallpox/pneumonia by the age of 3 years. Ten children were found to have at least two pathogens present. Moreover, both groups had a high prevalence and activity of EBV. These findings provide new insights into the carriage of pathogens among children with MIH, providing new information for parents, scientists, and healthcare professionals.

show abstract

Section: Discussionmentioning

confidence: 99%