Asymptomatic primary hyperparathyroidism: a surgical perspective

The Effect of Parathyroidectomy on Bone Fracture Risk in Patients With Primary Hyperparathyroidism

“…Hip fractures have been shown to shorten life expectancy, 17,18 and only half of patients who experience this injury will return to their previous level of functionality and independence. 19 Because parathyroidectomy is a safe operation, with current morbidity estimated at 1% to 3%, 20,21 it is an extremely attractive therapeutic modality for patients with PHPT to reduce hip fracture risk and the significant health burden associated with hip fracture.…”

Paradigm Shift in the Surgical Management of Multigland Parathyroid Hyperplasia

“…[1][2][3] Regardless of etiology, parathyroidectomy is the sole curative treatment option for PHPT; it improves symptoms and bone density, enhances quality of life, and resolves metabolic complications. 4 Traditional parathyroid surgery encompassed bilateral cervical exploration to identify all parathyroid glands and resect the enlarged, hyperfunctioning gland(s). Improvements in preoperative localization modalities with a corresponding surge toward less invasive interventions led to the development of focused, limited, minimally invasive parathyroidectomy (MIP) explorations.…”

Primary Hyperparathyroidism. Update on Pathophysiology, Clinical Presentation and Surgical Treatment

“…In spite of several studies indicating a positive effect of surgery on this kind of symptoms (19)(20)(21)(22), the recent workshop stated that "they should not be regarded as sole criteria for surgery. Depending upon the clinical circumstances, however, the clinician might want to weigh them in the overall consideration of the patients' presenting clinical profile" (2).…”