Asymptomatic Mild Intermittent Proteinuria. A Percutaneous Renal Biopsy Study

Renal Biopsy: Current Views and Controversies

“…Many would agree that reproducible or 'fixed' orthostatic proteinuria or per sistent proteinuria of less than I g/24 h when accompanied by normal renal function, blood pressure, urine sediment, and intravenous urogram, are not indications for biopsy, provided there is no evidence to suggest the syndrome of interstitial nephritis. The tissue obtained is frequently normal, or the abnormality is nonspecific and prognosis is favorable [121][122][123][124][125]. The 42-to 50-year follow-up of 6 of Thomas Addis' patients with postural proteinuria by Rytand andSpreiter [ 126] is reassuring as this study showed no evid ence of progressive disease.…”