Asymptomatic isthmico-cervical uterine perforation with IUD – our experience and literature review

Sparić, Radmila; Dotlić, Jelena; Mirković, Ljiljana; Stamenkovic, Jelena; Kotlica, B. Kastratovic; Nejković, Lazar; Babovic, Ivana R.; Malvasi, Antonio; Tinelli, Andrea

doi:10.12891/ceog3171.2016

Cited by 7 publications

(15 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The first is perforation at the installation time and can be diagnosed with acute pelvic pain, bleeding, or loss of cords. The second expected mechanism is uterine perforation, which occurs gradually and spontaneously in the presence of risk factors explained by further developments, so that it can be asymptomatic (10,11).…”

Section: Discussionmentioning

confidence: 99%

Calculus Formation in Bladder from Migrated Intrauterine Devices

Wijaya

Seputra²,

Daryanto³

et al. 2022

JKB

View full text Add to dashboard Cite

Migration of the intrauterine device (IUD) into the bladder has been a rare case. There were reported 31 cases of IUD migration into the bladder until 2006. Although IUD migration is asymptomatic, it should be removed to prevent complications such as pelvic abscess, bladder or intestinal rupture, and adhesion. A 52-year-old woman came to the urology clinic with pyuria since the previous 3 months. She had a history of IUD insertion in 1982; and two months later, she got pregnant. Since 2015, she has suffered from dysuria but has never been treated and has worsened in the past 3 months. On physical examination, tenderness was found in the suprapubic region. The results of urinalysis showed pyuria and hematuria. The ultrasonography findings, there were large bladder stones. An abdominal x-ray revealed the presence of a bladder stone with the IUD tail. Vesicolithotomy was performed and the IUD was found attached to an 11x7 cm bladder stone. The patient had a good postoperative condition without any special complications. The IUD in the bladder is a medium for forming secondary bladder stones. Most cases of IUD migration are caused by a lack of evaluation after the installation procedure. This case suggested that the physician should be more careful in carrying out the installation procedure. It is necessary to evaluate the location of the IUD after installation to prevent further patient complications.

show abstract

Section: Discussionmentioning

confidence: 99%

Calculus Formation in Bladder from Migrated Intrauterine Devices

Wijaya

Seputra²,

Daryanto³

et al. 2022

JKB

View full text Add to dashboard Cite

show abstract

“…Most IUD perforations are primary and occur during insertion in 0.4–1.1 per 1000 procedures, while secondary perforations are challenging to identify eight weeks or more after application [ 9 , 15 , 16 ]. Occurring later after the insertion, the migration of an IUD into the peritoneal cavity as a form of secondary perforation can lead to damage of the internal organs [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

“…It has been stated that women experiencing IUD perforations are usually multiparas in their early thirties and that for specific secondary perforations, abnormally arranged myometrial fibres and contractions of the uterus represent contributing factors [ 9 , 15 ]. This is also the case of the woman described above, who was younger than 30 years old and had a relevant obstetrical history with respect to potential disruption of the myometrium architecture.…”

Section: Discussionmentioning

confidence: 99%

“…There is scarce data in the literature regarding perforation occurring years after IUD placing, with the median time for diagnosis being approximately 5 months [ 15 ]. In our specific case, the patient recalled an IUD placement 2 years prior to the moment of the current admission but without any exceptional events associated.…”

Section: Discussionmentioning

confidence: 99%

“…In our specific case, the patient recalled an IUD placement 2 years prior to the moment of the current admission but without any exceptional events associated. A possible explanation for the incidental diagnosis of IUD perforation resides in the fact that most of the time, only mild symptoms can be identified during perforation: pelvic pain and abnormal bleeding; the uterine wall defect usually heals by itself, while one third of the patients can be completely asymptomatic—in this context, the diagnosis is established retrospectively, usually secondary to an unintended pregnancy [ 15 , 17 ].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Ectopic Intrauterine Device Revealed by Ureteral Colic in a 37-Week Pregnant Woman: Case Report

et al. 2022

View full text Add to dashboard Cite

Copper T intrauterine devices (IUDs) are a popular long-acting reversible contraceptive method. The most common reasons for contraceptive failure are expulsion and extrauterine migration. We report a case of a 28-year-old female, G13P3, 37 weeks pregnant, who presented to the hospital for left abdominal flank pain. The patient was admitted for treatment of left ureteral colic. The woman went into labour, and Caesarean Section was performed due to foetal distress. During the surgery, an inspection of the peritoneal cavity revealed a copper IUD embedded in the granulous tissue located in the left lateral abdominal region, which was extracted. No uterine scar tissue could be identified macroscopically. The migration of an IUD in the abdominal cavity is a rare finding, and coexistence with third-trimester pregnancy is an infrequent but serious event due to potential visceral complications. Higher gravidity can be associated with an increased risk of IUD migration in women with a non-scarred uterus.

show abstract

Preparation of Artemisia Turcomanic Encapsulated Niosomal Nanocarriers and Evaluation of Anticancer Activities and Apoptosis Gene Expression Analysis in HeLa Cells

Eslamian

Keshtmand

Hesampour

2023

Chemistry & Biodiversity

View full text Add to dashboard Cite

Artemisia turcomanic as a natural antibacterial agent, exhibited significant antibacterial effect in the treatment against cancer. This study is the first to investigate size, encapsulation efficiencies, release behavior of Artemisia turcomanic loaded niosomal nanocarriers, and the anticancer effect of niosomal nanocarriers by MTT assay, flow cytometry, and real time (on HeLa cell lines). When the molar ratio of cholesterol: surfactant was 1 : 2 and the liquid content was 300 μmol, the highest percentage of entrapment efficiency was 83.25 %. Moreover, niosomal formulation showed a pH-dependent release; a slowrelease profile in physiological pH (7.4), and a more significant release rate at acidic conditions (pH = 5.4). In addition, The apoptotic rate of Artemisia loaded niosomes on HeLa cell lines was higher than free extract and pristine niosome. Also, reduction in the expression levels of Bcl2, caspase-3, and p53 genes and increase in the expression level of BAX after treatment with Artemisia turcomanic-loaded niosomes were more significant than those after treatment with free Artemisia turcomanic and blank niosome. The cytotoxicity results of samples presented that Artemisia turcomanic loaded niosomes are more beneficial in the death of HeLa cell lines.

show abstract

Asymptomatic isthmico-cervical uterine perforation with IUD – our experience and literature review

Cited by 7 publications

References 11 publications

Calculus Formation in Bladder from Migrated Intrauterine Devices

Calculus Formation in Bladder from Migrated Intrauterine Devices

Ectopic Intrauterine Device Revealed by Ureteral Colic in a 37-Week Pregnant Woman: Case Report

Preparation of Artemisia Turcomanic Encapsulated Niosomal Nanocarriers and Evaluation of Anticancer Activities and Apoptosis Gene Expression Analysis in HeLa Cells

Contact Info

Product

Resources

About