Asymptomatic Inflammatory Bowel Disease Presenting With Mucocutaneous Findings

Galbraith, Sheila S.; Drolet, Beth A.; Kugathasan, Subra; Paller, Amy S.; Esterly, Nancy B.

doi:10.1542/peds.2004-2281

Cited by 65 publications

(62 citation statements)

References 18 publications

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“…The latter represents a specific marker of ulcerative colitis (8). Macrocheilia, cobblestoning of oral mucosa, deep linear ulcers of buccal vestibules, and polypoid mucosal tags are considered specific and pathogonomic for CD (1,2,11). Nonspecific changes include angular cheilitis, aphthous stomatitis and pyostomatitis vegetans (1).…”

Section: Discussionmentioning

confidence: 99%

“…Dental erosion, halitosis, odynophagia, dysphagia, high prevalence of caries, granulomatous and autoimmunelike changes in minor salivary glands, and reduced salivation have also been reported (12). Table 2 Oral granulomatosis is a common manifestation in patients with IBD and is typified by recurrent or persistent swelling of the lips, cheeks, gingivae, or oral mucosa with characteristic noncaseating granulomas on histologic examination (11). The lips are the most frequent site of involvement; the labial tissues demonstrate a nontender, persistent swelling that may involve one or both lips (13).…”

Section: Oral Manifestations Of Patient With Ibdmentioning

confidence: 99%

“…The lips are the most frequent site of involvement; the labial tissues demonstrate a nontender, persistent swelling that may involve one or both lips (13). Many patients with orofacial granulomatosis do eventually develop gastrointestinal disease consistent with Crohn's disease (11).…”

Section: Oral Manifestations Of Patient With Ibdmentioning

confidence: 99%

“…Aphthous ulcers are considered by many to be non-specific, as they can be seen in up to 20% of the general population; however aphtae are usually more extensive and persistent when associated with IBD (11). If a patient develops IBD during adulthood but has a history of recurrent aphthous ulcerations since adolescence, it is likely that the aphthous ulcers represent a coincident process that may be exacerbated by IBD or its management.…”

Section: Aphthous Ulcersmentioning

confidence: 99%

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Dental management of patients with inflammatory bowel disease

2010

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Ulcerative colitis and Crohn's disease are the most common forms of inflammatory bowel disease (IBD), both of unknown aetiology. These conditions are characterised by the chronic and recurrent inflammation of different parts of the gastrointestinal tract, but while in CD, chronic inflammation may affect any part of the gastrointestinal tract, in UC, mucosal inflammatory changes are confined to the colon. IBD is currently on the increase, and it is important for the dental professional to be familiar with the condition as patients with IBD may present oral manifestations of the underlying disease. Such manifestations of IBD may precede the onset of intestinal radiographic lesions by as much as a year, or even more. Treatments used to manage IBD can affect the delivery of routine dental care.

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Section: Discussionmentioning

confidence: 99%

Section: Oral Manifestations Of Patient With Ibdmentioning

confidence: 99%

Section: Oral Manifestations Of Patient With Ibdmentioning

confidence: 99%

Section: Aphthous Ulcersmentioning

confidence: 99%

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Dental management of patients with inflammatory bowel disease

2010

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“…[1][2][3][4][5] Perianal lesions may be the only symptom present at the diagnosis of Crohn's disease and can precede other symptoms by years. [5][6][7] In addition, perianal lesions at presentation are more common in children than in adults. 8 Due to their heterogeneous appearance, perianal lesions of Crohn's disease can be mistaken for benign lesions.…”

mentioning

confidence: 99%