Asymptomatic hyponatremia precipitated by COVID-19 pneumonia

Chittal, Abhinandan; Rao, Shiavax J.; Lakra, Pallavi; Zulty, Mary

doi:10.1080/20009666.2021.1979738

Cited by 4 publications

(5 citation statements)

References 3 publications

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“…A sudden drop in serum Na+ can overwhelm the capacity of the brain to regulate cell volume, leading to cerebral edema, seizures, and death. Hyponatremia, both asymptomatic and acute symptomatic, has been reported to be associated with COVID-19 in many case reports [12][13][14].…”

Section: Discussionmentioning

confidence: 99%

Hiccups and Acute Symptomatic Hyponatremia: A Rare Manifestation of COVID-19

Pandey¹,

Pandey²,

Andrews³

2022

Cureus

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We report a rare case of a patient presenting with a very unusual manifestation of coronavirus disease 2019 .A 62-year-old male presented to the emergency department (ED) with complaints of headache, nausea, vomiting, and intractable hiccups for two days. Laboratory results showed that he had profound hyponatremia (Na+: 103 mEq/L) and hypokalemia (K+: 2.3 mEq/L) with a positive RT-PCR for COVID-19. He was treated with an intravenous (IV) bolus of 3% saline solution followed by continuous infusion.The patient was discharged after eight days when his electrolytes returned to normal, and a significant symptomatic relief was achieved.

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Section: Discussionmentioning

confidence: 99%

Hiccups and Acute Symptomatic Hyponatremia: A Rare Manifestation of COVID-19

Pandey¹,

Pandey²,

Andrews³

2022

Cureus

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“…Hyponatremia both asymptomatic and acute symptomatic has been reported to be associated with Covid-19 in many case reports. [11], [12], [13] Hyponatremia in Covid-19 can be caused by either SIADH or in ammatory cytokines, IL-6, or a combination of both. [14] This is the rst case that reports upon both acute symptomatic hyponatremia and hiccups to be present simultaneously, in a Covid-19 patient.…”

Section: Discussionmentioning

confidence: 99%

Hiccups and Acute Symptomatic Hyponatremia: A Rare Manifestation of COVID-19.

Pandey

2022

Preprint

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We report a rare case of a COVID-19 patient presenting with very unusual symptoms.A 62-year-old male presented to ED with complaints of headache, nausea, vomiting, and intractable hiccups for the last 2 days. Labs showed that he had profound hyponatremia (Na+ 103 mEq/L) and hypokalemia (K+ 2.3 mEq/L). And RT-PCR was positive for COVID-19.He was treated with IV bolus of 3% Normal Saline and continuous infusion thereafter. The patient was discharged after 8 days when the electrolytes returned to normal and symptoms resolved.

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“…Several cases of hyponatremia secondary to SIADH in COVID-19 patients have been reported in the literature [6][7][8][9][10], with most of these cases being attributed to pneumonia as the underlying cause of SIADH [7][8][9][10]. However, others have also reported the development of SIADH in the absence of pneumonia [6].…”

Section: Discussionmentioning

confidence: 99%

“…While the Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) is thought to be the primary etiology in many cases [6][7][8][9][10], the underlying pathophysiology driving COVID-19-related hyponatremia can be varied, and a broader differential should be considered while assessing such patients. A thorough and systematic assessment is required to pinpoint the correct etiology and instigate the appropriate corrective therapy.…”

Section: Introductionmentioning

confidence: 99%

Hyponatremia in COVID-19 Is Not Always Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH): A Case Series

Javaid¹,

Shan²,

Frederick³

et al. 2022

Cureus

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Hyponatremia is a common complication in COVID-19-positive patients and is associated with significant mortality and morbidity. Several cases of COVID-19-related hyponatremia secondary to the Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH) have been reported in the literature, which might suggest that SIADH is almost always the underlying cause of hyponatremia in COVID-19 infections. However, COVID-19-related hyponatremia can have diverse underlying etiologies, similar to hyponatremia in non-COVID-19 patients, and requires a thorough assessment to reach a correct diagnosis and implement appropriate management.

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Asymptomatic hyponatremia precipitated by COVID-19 pneumonia

Cited by 4 publications

References 3 publications

Hiccups and Acute Symptomatic Hyponatremia: A Rare Manifestation of COVID-19

Hiccups and Acute Symptomatic Hyponatremia: A Rare Manifestation of COVID-19

Hiccups and Acute Symptomatic Hyponatremia: A Rare Manifestation of COVID-19.

Hyponatremia in COVID-19 Is Not Always Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH): A Case Series

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