Asymptomatic bacteriuria (ASB) in pregnant women in Enugu, Nigeria

Ezeome, Ijeoma Victoria; Ikeme, A. C.; Okezie, OA; Onyebueke, E.A.

doi:10.4314/tjog.v23i1.14556

Cited by 18 publications

(31 citation statements)

References 0 publications

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“…This is similar to findings in Enugu,24 Benin,17 and Ilorin,9 although it is at variance with other studies 10,19. Enterococci has been noted as a significant bacterial isolate from women with UTI in pregnancy 4,10,18,19,24. This is in support of the postulation that there tends to be a shift in the percentages of micro organisms causing UTI in favor of Staphylococcus, Klebsiella, and P. mirabilis.…”

Section: Discussionsupporting

confidence: 90%

Antibiotic sensitivity pattern of uropathogens from pregnant women with urinary tract infection in Abakaliki, Nigeria

Onoh¹,

Umeora²,

Egwuatu³

et al. 2013

IDR

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BackgroundUrinary tract infection (UTI) is a common bacterial infection during pregnancy and a significant cause of perinatal and maternal morbidity and mortality. The causative bacteria have remained virtually the same although with variations in individual prevalence. There has been an increasing resistance by these bacteria to the commonly available antibiotics.ObjectivesTo determine the prevalence of UTI, the common causative bacteria, and their antibiotic sensitivity pattern among pregnant women with UTI.MethodologyThis is a descriptive study that was carried out at the Obstetrics Department of two tertiary institutions in Abakaliki, Ebonyi State, Nigeria (Federal Medical Center and Ebonyi State University Teaching Hospital) over a period of 12 months. Midstream urine specimens from selected pregnant women with clinical features of UTI were collected for microscopy, culture, and sensitivity. The results were analyzed with the 2008 Epi Info™ software.ResultsA total of 542 pregnant women presented with symptoms of UTI and were recruited for the study over the study period. Of the 542 pregnant women, 252 (46.5%) had significant bacteriuria with positive urine culture and varying antibiotic sensitivity pattern. The prevalence of symptomatic UTI was 3%. Escherichia coli was the most common bacteria isolated with a percentage of 50.8%. Other isolated micro organisms included Stapylococcus aereus (52 cultures, 20.6%), Proteus mirabilis (24 cultures, 9.5%), S. saprophyticus (18 cultures, 7.1%), Streptococcus spp. (14 cultures, 5.6%), Citrobacter spp. (5 cultures, 2.0%), Klebsiella spp. (4 cultures, 1.6%), Enterobacter spp. (4 cultures, 1.6%), and Pseudomonas spp. (3 cultures, 1.2%). Levofloxacin had the highest overall antibiotic sensitivity of 92.5%. Others with overall antibiotic sensitivity pattern greater than 50% included cefpodoxime (87.3%), ofloxacin (77.4%), ciprofloxacin (66.7%), ceftriaxone (66.7%), and gentamicin (50.8%).ConclusionE. coli was the most common etiological agent of UTI in pregnancy with Enterococcus (Staphylococcus) gaining prominence. Cephalosporin and quinolones were shown to be very effective against the organisms causing UTI in these pregnant women.

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Section: Discussionsupporting

confidence: 90%

Antibiotic sensitivity pattern of uropathogens from pregnant women with urinary tract infection in Abakaliki, Nigeria

Onoh¹,

Umeora²,

Egwuatu³

et al. 2013

IDR

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“…The prevalence of symptomatic and asymptomatic bacteriuria was observed to be 17.9% and 13%, respectively. A study in Enugu, Nigeria reported similar fi ndings (Ezeome et al 2006). However, the prevalence of asymptomatic bacteriuria observed in our study is signifi cantly high compared to those reported in developed countries and this is likely to be attributed to low socio-economic status (Gilstrap et al, 2001, Santos et al, 2002Sheikh et al, 2000).…”

Section: Discussioncontrasting

confidence: 55%

Prevalence of urinary tract infection among pregnant women at Bugando Medical Centre, Mwanza, Tanzania

Masinde¹,

Gumodoka²,

Kilonzo³

et al. 2009

Tanzania J Hlth Res

134

111

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Urinary tract infections (UTI) are the most common bacterial infections during pregnancy and these infections. Untreated UTI can be associated with serious obstetric complications. This cross-sectional study was carried out to determine the prevalence of UTI among symptomatic and asymptomatic pregnant women attending Bugando Medical centre (BMC) in Mwanza, Tanzania. A total of 247 pregnant women were enrolled, of these 78 (31.5%) were symptomatic and 169 (68.4%) asymptomatic. UTI was diagnosed using mid stream urine (MSU) culture on standard culture media and urinalysis was done using rapid dip stick. The prevalence of bacteriuria among symptomatic and asymptomatic pregnant women were 17.9% and 13.0% respectively, with no signifi cant difference between the two groups (p= 0.307). Using univariate analysis there was no association of parity (p=0.825), gestational age (p=0.173), education (p=0.615), age (p=0.211) and marital status (p=0.949) with bacteriuria. The sensitivity and specifi city of urine dipstick was 38.9% and 86.7% respectively. Escherichia coli (47.2%) and Enterococcus spp (22.2%) were the most commonly recovered pathogens. The rate of resistance of Escherichia coli to ampicillin, tetracycline, sulfamethaxazole/trimethoprim, gentamicin, ciprofl oxacin, nitrofurantoin, ceftriaxone, and imipenem were 53%, 58.8%, 64.7%, 5.9%, 11.8%, 5.9%, 29.4% and 0%, respectively. In conclusion, asymptomatic bacteriuria among pregnant women is prevalent in our setting and majority of Escherichia coli are resistant to ampicillin, tetracycline, SXT and ceftriaxone. Due to low sensitivity of rapid dip stick, routine urine culture and susceptibility testing is recommended to all pregnant women at booking.

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“…The prevalence of ASB in normal pregnant population has been quoted to range from 2-10% [9][10][11] and in Nigeria a prevalence of 4-14.1% have been documented. 12 Prevalence has been found to be, generally, increased with age, sexual activity and parity.…”

Section: Introductionmentioning

confidence: 99%