Asymptomatic bacteriuria among antenatal care women in a tertiary hospital in Benin, Nigeria

Ojide, Chiedozie Kingsley; Wagbatsoma, VA; Kalu, Eziyi Iche; Nwadike, Victor

doi:10.4103/2348-0149.144841

Cited by 9 publications

(12 citation statements)

References 22 publications

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“…Educational level attained may be an indicator of the socioeconomic status of the women. Lower levels of education and low socioeconomic status have been related to higher prevalence of ABU in others studies [5, 20]. Another predictor of bacteriuria in pregnancy identified in this study was past history of UTI.…”

Section: Discussionsupporting

confidence: 59%

Clinical presentation, risk factors and pathogens involved in bacteriuria of pregnant women attending antenatal clinic of 3 hospitals in a developing country: a cross sectional analytic study

Nguefack

Ebongue

Chokotheu

et al. 2019

BMC Pregnancy Childbirth

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Background Pregnancy increases the risk of recurrent bacteriuria and acute pyelonephritis which is associated with significant maternal and fetal risks. The prevalence of bacteriuria varies worldwide. Clinical diagnosis is challenging since it is usually mistaken for normal physiological changes during pregnancy. This study aims to determine the prevalence, clinical presentation, risk factors and microorganism responsible for bacteriuria in pregnant women of Douala city, Cameroun. Methods A cross-sectional study was conducted in 3 hospitals of Douala from January to April 2015. We consecutively recruited all consented pregnant women aged 18 years and above attending antenatal clinics. Socio-demographic characteristics, medical and obstetrical past history, clinical signs and obstetric characteristics of the index pregnancy were collected. Thereafter, urine were collected aseptically and subjected to routine macroscopy, microscopy examination and culture. The culture was obtained by inoculation of 10 μl of urine on the appropriate medium. Identification of pathogens was done automatically using the VITEK2 ™ (BioMérieux- France). Data were processed using the Statistical Package for the Social Sciences (SPSS) 18. Statistics were descriptive and analytic; Odds ratios were calculated. Associations between variables and bacteriuria were conducted using the Chi squared test and the fisher exact probability. Associations with p -values < 0.05 were considered statistically significant. Results Overall, 354 pregnant women were enrolled with mean of age 28.18 ± 4.4. The prevalence of significant bacteriuria was 9.9% (35 out of 354). The prevalence of bacteriuria in women who were asymptomatic was 5.7%. Cystitis and pyelo-nephritis were observed in 3.6 and 0.6% respectively. The most commonly isolated organism was Escherichia coli ( E. coli) : 48.6%. History of Urinary Tract Infection (UTI) ( p = 0.035, OR = 2.183, CI = 1.055–4.518) was significantly associated with bacteriuria. High level of education was protective. Conclusions Bacteriuria was frequent in pregnant women and significantly increased with the past history of UTI and low level of education. Asymptomatic bacteriuria was more common. E coli was the most frequent uropathogen. Education and proper treatment of UTI should be provided to reduce the burden of this pathology in order to prevent its severe complications.

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Section: Discussionsupporting

confidence: 59%

Clinical presentation, risk factors and pathogens involved in bacteriuria of pregnant women attending antenatal clinic of 3 hospitals in a developing country: a cross sectional analytic study

Nguefack

Ebongue

Chokotheu

et al. 2019

BMC Pregnancy Childbirth

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“…4,28,32 There is an increased risk for UTI, beginning from 6 th week and the peak levels were observed from 22 nd to 24 th weeks. 11,16,29 The increased risk of having UTI during pregnancy is mainly due to past history of UTIs and other risk factors includes-lower socio economic status, individual hygiene, sickle cell trait and anemia, increased parity or age, number of child births, number of inter-courses per week, and lack of prenatal care. 23,27 The functional urinary tract abnormalities and diabetes mellitus can also increase susceptibility to UTIs during pregnancy.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of UTI among Pregnant Women and Its Complications in Newborns

Ranjan¹,

Sridhar²,

Matta³

et al. 2017

IJOPP

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Urinary Tract Infections (UTI) are mainly caused by the presence and growth of microorganisms in the urinary tract, which are the single commonest bacterial infections of all age groups and especially in pregnancy. The main objective of this study is to determine the Prevalence of UTI among pregnant women and complications in their newborns. An observational study was carried out over a period of 6 months. A total of 120 pregnant women were enrolled .UTI was diagnosed based on urinalysis reports. With the help of data collection form demographic data were collected. Out of 120 pregnant women, 35% of them had urinary tract infection. It is mostly observed high in age group of <25yrs, Primigravida, winter season and during Third trimester of pregnancy. The commonest causative organism was found to be E.coli (50%).The weight of newborn infants of mothers afflicted with UTI were significantly not lowered compared to newborns of healthy women. The prevalence rate of urinary tract infection (UTI) during pregnancy is high. So it is important to do routine screening of all pregnant women for significant bacteriuria to reduce the complications on both maternal and fetal health.

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“…[48] 2016 Nigeria West Clean catch midstream urine cross sectional 120 27 6 22.5 (15.0, 30.0) 35 Ojide CK., et al. [49] 2020 Nigeria West Clean catch midstream urine cross sectional 265 28 7 10.6 (6.9, 14.3) 36 Oko JO., et al. [50] 2017 Nigeria West Clean catch midstream urine cross sectional 350 83 8 23.7 (19.2, 28.2) 37 Okon KO., et al.…”

Section: Study Characteristicsmentioning

confidence: 99%

“… 15 1801 6.2 (3.8 - 8.6) 75.3 < 0.001 14 Pseudomonas spp. [ 14 , [16] , [17] , [18] , 20 , [28] , [29] , [30] , 33 , 38 , 44 , 45 , 48 , 51 , 56 , 58 ] 16 1375 4.7 (3.6 - 5.8) 31.8 0.108 15 C. freundii [ 18 , 28 , 55 , 56 ] 4 173 3.3 (0.6 - 5.9) 0 0.455 16 Enterococcus [ 16 , 20 , 32 , 35 , 42 , 49 , 59 , 60 , 61 ] 9 345 3.1 (1.2 - 5.1) 6.7 0.379 CoNS*= Coagulase negative Staphylococci . …”

Section: Publication Biasmentioning

confidence: 99%

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Bacterial Profile and asymptomatic bacteriuria among pregnant women in Africa: A systematic review and meta analysis

et al. 2021

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Background: Different physiologic changes that occur during pregnancy, such as Hydroureter, dilatation of the renal pelvis, glycosuria and aminoaciduria, and low urine production predispose pregnant women for ascending urinary tract infection. Globally, 2% to 15% of the pregnant women have urinary tract infection without specific symptoms. Therefore, this study aimed to estimate the prevalence of asymptomatic bacteriuria (ABU) in pregnant women in Africa. Methods: Systematic search of published studies done on PubMed, EMBASE, Web of Science, SCOPUS, Psy-chInfo, CINAHL, and google scholar for gray literature. All published observational studies until October 30, 2020 were included. This meta-analysis follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Quality of studies was assessed by modified Newcastle-Ottawa Scale (NOS). Meta-analysis was carried out using a random-effects method with the double arcsine transformation approach using the STATA TM Version 14 software. Trim and fill analysis was done to correct presence of significant publication bias. The study protocol is prospectively registered on PROSPERO, registration number CRD42020212601. Findings: From 3393 obtained studies, 48 studies from 12 African countries involving 15, 664 pregnant women included in this Meta-analysis. The overall pooled prevalence of asymptomatic bacteriuria among pregnant women in Africa after correction for publication bias by trim and fill analysis was found to be 11.1% (95% CI: 7.8, 14.4). The most common bacterial isolates involved in the etiology of ABU was Escherichia coli with pooled prevalence 33.4% (95% CI: 27.3 -39.4) Interpretation: Asymptomatic bacteriuria is substantial among pregnant women in Africa. Therefore, all pregnant women should be tested for the presence of asymptomatic bacteriuria. A screening program must be based not only on the incidence but also on a cost-efficacy evaluation and a microbiological evaluation.

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Asymptomatic bacteriuria among antenatal care women in a tertiary hospital in Benin, Nigeria

Cited by 9 publications

References 22 publications

Clinical presentation, risk factors and pathogens involved in bacteriuria of pregnant women attending antenatal clinic of 3 hospitals in a developing country: a cross sectional analytic study

Clinical presentation, risk factors and pathogens involved in bacteriuria of pregnant women attending antenatal clinic of 3 hospitals in a developing country: a cross sectional analytic study

Prevalence of UTI among Pregnant Women and Its Complications in Newborns

Bacterial Profile and asymptomatic bacteriuria among pregnant women in Africa: A systematic review and meta analysis

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