Asymmetrical Distribution of Implantation Sites in the Rat Uterus

Buchanan, G. D.

doi:10.1095/biolreprod11.5.611

Cited by 12 publications

(9 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our data also show more large, healthy follicles in the right ovary in intact rats bearing both ovaries. This corroborates an earlier observation of Buchanan (1974). Our data also suggests that function of the right ovary is more dependent than the left ovary on intact vagal connections.…”

Section: Av-lulo (4)supporting

confidence: 93%

The effects of vagotomy on compensatory ovarian hypertrophy and follicular activation after unilateral ovariectomy

et al. 1986

View full text Add to dashboard Cite

Following unilateral ovariectomy in the rat, the remaining ovary undergoes rapid compensatory changes including an increase in the number of antral follicles (follicular activation) and an increase in ovarian weight (compensatory ovarian hypertrophy). The ovary is innervated by the vagus nerve (Burden et al., 1983). In the present study, the effects of right and left cervical vagotomy and abdominal vagotomy on follicular activation and compensatory ovarian hypertrophy in the remaining right or left ovary were compared 15 days after unilateral ovariectomy. Neither right nor left cervical vagotomy affected compensatory ovarian hypertrophy of the right or left ovaries but abdominal vagotomy depressed compensatory ovarian hypertrophy in both the right and left ovaries. Left cervical vagotomy did not inhibit follicular activation, but right cervical vagotomy prevented follicular activation in the right but not left ovary. Also, abdominal vagotomy inhibited follicular activation in the right but not the left ovary. In animals with both ovaries which were subjected to the left or right cervical vagotomy or abdominal vagotomy follicular counts in both right and left ovaries were similar. Collectively, these data indicate that the vagus nerve participates in follicular activation after unilateral ovariectomy. The data also indicate that the right ovary is more dependent on vagal influences for follicular activation than the left ovary.

show abstract

Section: Av-lulo (4)supporting

confidence: 93%

The effects of vagotomy on compensatory ovarian hypertrophy and follicular activation after unilateral ovariectomy

et al. 1986

View full text Add to dashboard Cite

show abstract

“…The literature provides multiple examples of lateral asymmetry of both mammalian ovaries and uterine horns [4][5][6]. In rats, the left uterine horn contains fewer implantation sites than the right horn [7]. A larger number of embryos are gestated in the right uterine horn in mice [8], and in hamsters a greater number of sperm are present in the right uterine horn after mating [9].…”

Section: Introductionmentioning

confidence: 99%

Sex Ratio of Bovine Embryos and Calves Originating from the Left and Right Ovaries1

Hylan

Giraldo

Carter

et al. 2009

Biology of Reproduction

View full text Add to dashboard Cite

An asymmetric distribution of the sexes within the left and right uterine horns has been described in multiple species. A series of experiments were conducted to evaluate the sex ratio (% male) of calves gestated in the left and right uterine horns, as well as the sex ratio of embryos originating from the left and right ovaries of cattle. The sex ratio of calves gestated in the right uterine horn of naturally mated cows was significantly higher compared with the sex ratio of calves gestated in the left uterine horn. In addition, the sex ratio of the left and right uterine horns differed significantly from parity. The sex ratio of embryo transfer calves born following transfer to the left and right uterine horns was not significantly different. Additionally, the proportion of male embryos collected from the right uterine horns was significantly greater than from the left uterine horns of superovulated cows. The sex ratio of embryos collected from the left and right uterine horns of unilaterally ovariectomized cows was not significantly different. However, more female than male embryos were produced when left ovary oocytes fertilized in vitro. In conclusion, the results of these experiments demonstrate that a significantly greater proportion of males are gestated in the right uterine horn of cattle and a greater proportion of females in the left. Additionally, the data indicate that sex-specific selection pressure may be applied to embryos by ovarian factors rather than by the uterine environment.

show abstract

“…In hamsters, the right uterine horn contains more sperm after mating (O and Chow, 1987) than does the left. In Norway rats, the right uterine horn has more implantation sites (Buchanan, 1974) and, in mice, sustains more live embryos than does the left (Wiebold and Becker, 1987).…”

Section: Introductionmentioning

confidence: 99%

“…The right ovary of rats is larger (Mittwoch and Kirk, 1975) than the left and in rats, hamsters and mice the right ovary has more corpora lutea (Buchanan, 1974;O and Chow, 1987; Wiebold and Becker, 1987) than does the left. In humans, the right ovary is more prone to tumours (Willis, 1967) and, in shrews, has fewer follicles (Mohanty and Chainy, 1992) than does the left.…”

Section: Introductionmentioning

confidence: 99%

Differences in the sex ratios of offspring originating in the right and left ovaries of Mongolian gerbils (Meriones unguiculatus)

Clark

Ham²,

Galef³

1994

Reproduction

View full text Add to dashboard Cite

Two experiments were undertaken to investigate the cause of the observed tendency of Mongolian gerbil dams to gestate more male than female fetuses in their right uterine horns and more female than male fetuses in their left uterine horns. It was found in Expt 1 that female gerbils that had both ovaries removed and portions of their right ovary placed in both ovarian capsules gestated significantly more male fetuses than did females that had both ovaries removed and portions of their left ovaries placed in both ovarian capsules. Expt 2 showed that female gerbils that had both their ovaries removed and then returned to their original locations gestated more males in their right uterine horns than in their left, while females that had the positions of their ovaries exchanged gestated more male fetuses in their left uterine horns than in their right. The data were consistent with the hypothesis that lateral asymmetries in gerbil ovaries rather than in gerbil uterine horns cause partial uterine segregation of gerbil fetuses by sex.

show abstract

Asymmetrical Distribution of Implantation Sites in the Rat Uterus

Cited by 12 publications

References 13 publications

The effects of vagotomy on compensatory ovarian hypertrophy and follicular activation after unilateral ovariectomy

The effects of vagotomy on compensatory ovarian hypertrophy and follicular activation after unilateral ovariectomy

Sex Ratio of Bovine Embryos and Calves Originating from the Left and Right Ovaries1

Differences in the sex ratios of offspring originating in the right and left ovaries of Mongolian gerbils (Meriones unguiculatus)

Contact Info

Product

Resources

About