2023
DOI: 10.1039/d3ra06955a
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Asymmetric total synthesis strategies of halichlorine and pinnaic acid

Lu Liu,
Minghua Jiang,
Qingkang Zhang
et al.

Abstract: Halichlorine and pinnaic acids are structurally related to natural alkaloids isolated from different marine organisms. This review summarizes the asymmetric synthesis strategies of halichlorine and pinnaic acid using a 6-azaspiro[4.5]decane skeleton as the key intermediate.

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