Asymmetric Synthesis of Pantolactone: Recent Advances
Zhi‐Hong Du,
Xiao‐Xiong Lv,
Ning Liu
et al.
Abstract:(R)‐Pantolactone, an intermediate in the syntheses of Vitamin B5 and coenzyme A, is an important chiral molecule often used as a food additive, chiral auxiliary, and chiral starting material for organic transformations. Enantioenriched pantolactones are predominantly produced by biological fermentation and chemical synthesis approaches. Herein, we present a review of recent developments in the asymmetric synthesis of pantolactone via different methods, and systematically summarize the characteristics and advan… Show more
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