Asymmetric nucleophilic addition to vinylphosphonamidates (Part IV)

Abstract

Both stereoisomers of 6(R)-methyl-2-propenyl-1,3,2-oxazaphosphorinane-2-oxide 5a and 5b are prepared as single enantiomers. The configurations of the phosphorus atoms in the two compounds are deduced by NMR. The stereoselectivity in the addition of the phenyl carbanion to 5a and 5b are discussed.