Asymmetric hydrogenation in aqueous–organic two-phase solvent systems using rhodium complexes of sulphonated phosphines

Alario, F.; Amrani, Y.; Colleuille, Y.; Dang, T. P.; Jenck, J.; Morel, D.; Sinou, Denis

doi:10.1039/c39860000202

Cited by 39 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The most applied alternative media concern aqueous systems, ionic liquids and supercritical fluids. In water, Sinou and co-workers [18,19], reported a decrease of enantioselectivity using sulphonated phosphines. Good results were observed with sulphonated versions of CHIRAPHOS and PROPHOS ligands in water, but in general the tendency in this reaction medium is a enantioselectivity decrease in comparison with that obtained in organic solvents.…”

Section: Introductionmentioning

confidence: 99%

Rhodium complexes containing chiral P-donor ligands as catalysts for asymmetric hydrogenation in non conventional media

et al. 2011

View full text Add to dashboard Cite

Rhodium-catalysed asymmetric hydrogenation using P-donor ligands, such as new fluorinated (R)-BINOL and azadioxaphosphabicyclo[3.3.0]octane derivatives was carried out in different reaction media such as organic solvent (CH 2 Cl 2 ), ionic liquid ([BMI][PF 6 ]), supercritical carbon dioxide (scCO 2 ) and [BMI][PF 6 ]/scCO 2 mixture. The best enantioselectivities were obtained in neat [BMI][PF 6 ], allowing a recycling up to ten times without activity loss. However, the enantioselectivity was lost due to ligand leaching. The ionic liquid phase containing rhodium molecular species was supported on functionalized multi-walled carbon nanotubes in order to improve the recycling, but unfortunately the asymmetric induction was lost upon catalyst immobilization.

show abstract

Section: Introductionmentioning

confidence: 99%