Asthmavorstadium bei Patienten mit Rhinitis allergica

Bolpacic, Jasna; M, Bogić; Tadić, Jasmina; Spirić, Vesna Tomić; Perić-Popadić, Aleksandra; Sojic-Rajcic, Jasminka; Arandjelovic, Snezana; Stosović, R; Rašković, Sanvila; Lj, Stefanović

doi:10.5414/alp29261

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Local Allergic Rhinitis and Astma1

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2021

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“…For these reasons, asthma in these patients has been called local allergic asthma, in an effort to isolate a new phenotype of allergic asthma in individuals with non-atopic constitution [34]. These findings further confirm the concept of united airway diseases, by unequivocal evidence of the pathophysiological connection between LAR and local allergic asthma [35][36][37][38][39].…”

Section: Local Allergic Rhinitis and Astmamentioning

confidence: 75%

Local allergic rhinitis - a big challenge in clinical practice

Stosović

Spirić

2021

Srp Arh Celok Lek

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Local allergic rhinitis is a new rhinitis phenotype characterized by symptoms similar to allergic rhinitis, in non-atopic patients with a positive nasal allergen provocation test (NAPT). The disease is diagnosed in over 25% of non-atopic patients with rhinitis, marked as non-atopic rhinitis. It most often has perennial and severe symptoms and a progressive course. It is often associated with conjunctivitis and/or asthma. It is necessary to consider local allergic rhinitis in patients with non-atopic rhinitis. The gold standard for diagnosis is positive NAPT. Pharmacological therapy fails to stop the natural progression and development of comorbidities. Allergen immunotherapy reduces the symptoms, consumption of medicines and increases the tolerance to allergens responsible for local allergic rhinitis. New studies are needed to confirm curative and evaluate the preventive effects of allergen immunotherapy.

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Section: Local Allergic Rhinitis and Astmamentioning

confidence: 75%