Asthma Severity, Psychiatric Morbidity, and Quality of Life: Correlation with Inhaled Corticosteroid Dose

Bonala, Savithri B.; Pina, Desiderio; Silverman, Bernard A.; Amara, Sreenivasrao; Bassett, Clifford W.; Schneider, Arlene T.

doi:10.1081/jas-120023491

Cited by 46 publications

(46 citation statements)

References 39 publications

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“…Anxiety has higher prevalence among females. Coinciding with other studies [27,[30][31][32][33][34], we also observed greater psychiatric comorbidity in women.…”

Section: Interpretation Of Findings In Relation To Previously Publishsupporting

confidence: 63%

Asthma, Anxiety and Depression are they walking together? Cross- Sectional Descriptive Study

Flor-Escriche¹,

Poblet-Cortés²,

Lamarca-Fornell³

et al. 2016

Arch Pulmonol Respir Care

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Background/Objectives: The association between asthma and mental health disorders is well known, both anxiety and depression being the most common ones. The aim is to determine the proportion of anxiety and/or depression in an asthmatic population compared to a non-asthmatic one in a Primary Care centre. Secondary objectives: Assess the association between the severity of asthma and its level of control and anxiety and/or depression. Methods:Cross-sectional descriptive study, 317 patients diagnosed of asthma and 306 without asthma, aged between 17 to 70 years old, recruited from a primary care centre. Goldberg test was performed to detect anxiety and/or depression. Other variables analysed were: age, sex, previous diagnosis of anxiety and/or depression, associated chronic diseases, type of asthma and degree of its control.Results: 70% of the people in the asthmatic group were women and 52% in the non-asthmatic group. The mean age was of 43 (SD 16.89) and 48 (SD 14.09) years old, respectively. 57.1% had intermittent asthma. 62.7% of asthmatics had good control. Goldberg test in the group of asthmatic patients showed 51.1% (p = 0.0001) of anxiety and 57.4% (p = 0.0001) of depression. The results were adjusted for age and sex maintaining the association between asthma and anxiety with an OR = 1.8 (95% CI: 1.3-2.6) and depression OR = 2.1 (95% CI: 1.5 to 3.0). Patients with a higher level of asthma control had less anxiety (p = 0.002) and depression (p = 0.004). Conclusions:Asthmatic patients had more anxiety and depression. Higher asthma control was associated with less anxiety and depression.

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“…Anxiety has higher prevalence among females. Coinciding with other studies [27,[30][31][32][33][34], we also observed greater psychiatric comorbidity in women.…”

Section: Interpretation Of Findings In Relation To Previously Publishsupporting

confidence: 63%

Asthma, Anxiety and Depression are they walking together? Cross- Sectional Descriptive Study

Flor-Escriche¹,

Poblet-Cortés²,

Lamarca-Fornell³

et al. 2016

Arch Pulmonol Respir Care

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show abstract

“…2,3 Therefore, anxiety and depression may be relevant features of asthma. 4 Both emotional disorders may induce poor asthma outcomes: (1) impaired quality of life, 5 (2) frequent emergency department admissions and hospitalizations, 6 (3) severe asthma symptoms, 7 (4) high corticosteroid dosages, 8 (5) nonadherence to therapy, 9 and (7) even lethal attacks. 10 Inaccurate perception of severe asthma symptoms may negatively influence the asthma prognosis.…”

Section: Introductionmentioning

confidence: 99%

The impact of anxiety and depression on outpatients with asthma

Ciprandi

Schiavetti

Rindone

et al. 2015

Annals of Allergy, Asthma & Immunology

147

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“…Three studies have reported that anxiety was associated with increased use of prednisone [15][16][17] while other two studies found no significant relationship [18,34]. However, most were limited by cross-sectional designs and/or small sample sizes.…”

Section: Accepted M Manuscriptmentioning

confidence: 99%

“…In Asia , a recent case-control study [14] found a 3-fold higher risk of anxiety disorder in COPD than controls (18.3% vs 5.3%) in China, but no population-based cohort study has yet been reported in Asia. In addition, the association of prednisone with anxiety remains controversial with inconsistent results [15][16][17][18] with previous studies limited by cross-sectional design and small sample sizes. We describe what we believe to be…”

Section: Introductionmentioning

confidence: 99%

Chronic obstructive pulmonary disease and anxiety disorders: a nationwide population-based study in Taiwan

Hsieh

Lee

Tsai

et al. 2016

General Hospital Psychiatry

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Objective: Few studies have investigated the relationship between Chronic Obstructive Pulmonary Disease (COPD) and anxiety disorder outcomes. We sought to investigate the association in a large national sample. Results: Of the 59,902 subjects, 3951 were found to have anxiety disorders during a mean (SD) follow-up period of 5.5 (2.5) years. COPD, female, urban residence, lower dose of prednisone use, depressive disorders and higher outpatient visits were independent predictors of incident anxiety disorder. MethodsConclusions: COPD was associated with increased risk of an anxiety disorder diagnosis, independent of a number of potential confounding factors.

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Asthma Severity, Psychiatric Morbidity, and Quality of Life: Correlation with Inhaled Corticosteroid Dose

Cited by 46 publications

References 39 publications

Asthma, Anxiety and Depression are they walking together? Cross- Sectional Descriptive Study

Asthma, Anxiety and Depression are they walking together? Cross- Sectional Descriptive Study

The impact of anxiety and depression on outpatients with asthma

Chronic obstructive pulmonary disease and anxiety disorders: a nationwide population-based study in Taiwan

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