Asthma and lower respiratory symptoms in New York State employees who responded to the World Trade Center disaster

Mauer, Matthew P.; Herdt-Losavio, Michele L.; Carlson, G. Anders

doi:10.1007/s00420-009-0474-x

Cited by 10 publications

(6 citation statements)

References 29 publications

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“…Mauer et al (2010 a,b, and c) described long-term respiratory symptoms in NYS employees who were WTC responders on or after 9/11/2001. They were initially mailed self-administered questionnaires (initial, Year 1, and Year 2) and then they completed a telephone interview in Year 3.…”

Section: Populations With Work-related or Residential Exposures To Wtmentioning

confidence: 99%

Health effects of World Trade Center (WTC) Dust: An unprecedented disaster with inadequate risk management

Lippmann¹,

Cohen²,

Chen³

2015

Critical Reviews in Toxicology

100

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The World Trade Center (WTC) twin towers in New York City collapsed on 9/11/2001, converting much of the buildings’ huge masses into dense dust clouds of particles that settled on the streets and within buildings throughout Lower Manhattan. About 80–90% of the settled WTC Dust, ranging in particle size from ~2.5 μm upward, was a highly alkaline mixture of crushed concrete, gypsum, and synthetic vitreous fibers (SVFs) that was readily resuspendable by physical disturbance and low-velocity air currents. High concentrations of coarse and supercoarse WTC Dust were inhaled and deposited in the conductive airways in the head and lungs, and subsequently swallowed, causing both physical and chemical irritation to the respiratory and gastroesophageal epithelia. There were both acute and chronic adverse health effects in rescue/recovery workers; cleanup workers; residents; and office workers, especially in those lacking effective personal respiratory protective equipment. The numerous health effects in these people were not those associated with the monitored PM2.5 toxicants, which were present at low concentrations, that is, asbestos fibers, transition and heavy metals, polyaromatic hydrocarbons or PAHs, and dioxins. Attention was never directed at the very high concentrations of the larger-sized and highly alkaline WTC Dust particles that, in retrospect, contained the more likely causal toxicants. Unfortunately, the initial focus of the air quality monitoring and guidance on exposure prevention programs on low-concentration components was never revised. Public agencies need to be better prepared to provide reliable guidance to the public on more appropriate means of exposure assessment, risk assessment, and preventive measures.

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Section: Populations With Work-related or Residential Exposures To Wtmentioning

confidence: 99%

Health effects of World Trade Center (WTC) Dust: An unprecedented disaster with inadequate risk management

Lippmann¹,

Cohen²,

Chen³

2015

Critical Reviews in Toxicology

100

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“…8,9 Comparing residential with occupational exposures, we found new-onset LRS post-9/11 was slightly higher in NYS WTC responders than residents of affected areas. 1,2,5 Cough was the predominant LRS among both populations. 2,5…”

Section: Health Impacts Of the Wtc Disaster Among Nyc Residents And Rmentioning

confidence: 89%

“…Smoke exposure may have had a greater lower respiratory impact than resuspended dust. 5 Chronic bronchitis was identified as a persistent problem 5-years post-9/11. Participants with the highest exposures were more likely to experience increased severity of asthma and/or LRS.…”

Section: Health Impacts Of the Wtc Disaster Among Nyc Residents And Rmentioning

confidence: 99%

Article Commentary: Lessons Learned from the September 11th Disaster: A State Health Agency Perspective

Lin

Mauer

Jones

et al. 2012

Environ�Health�Insights

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The New York State Department of Health has conducted a number of studies over the past 10 years investigating health impacts related to the September 11, 2001 (9/11) disaster among New York City residents and New York State World Trade Center (WTC) responders. Efforts to evaluate the health effects of WTC exposures in these cohorts presented numerous challenges, including study design and associated concerns about bias, identifying the affected populations, gaining community support and participation, and determining the most appropriate clinical testing and follow-up approaches. The unique position of a state public health agency provided multiple points of support for these efforts. An overview of what was found and the lessons learned during the response to the 9/11 disaster is presented, from the viewpoint of a state public health agency.

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“…It is now well accepted that respirable pollutants after the WTC attack caused inhalation injury. [2][3][4][5][6][7][8][9][10][11][12][13][14] Biochemical, 38,39 physiologic, [2][3][4][5][6][7][8][9][10]12 and clinical [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16]40,41 Symptoms by AAT Combination There were no signifi cant differences in sex, age, race, ex-smoking status, work assignment, WTC exposure intensity, and pre- September 11, 2001, FEV 1 or FVC values among the three AAT phenotype combinations ( Table 4 ) or between workers with low vs normal serum AAT levels. Among workers with low serum AAT levels, cough persisted in a signifi cant number of individuals from 1 to 3 months to 4 years post- September 11, 2001.…”

Section: Discussionmentioning

confidence: 99%

Accelerated Spirometric Decline in New York City Firefighters With α;1-Antitrypsin Deficiency

Banauch

Brantly

Izbicki

et al. 2010

Chest

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Asthma and lower respiratory symptoms in New York State employees who responded to the World Trade Center disaster

Abstract: Moderately exposed responders may experience health impacts from exposures in later stages of a disaster. Exposure to smoke may have had a greater lower respiratory impact than resuspended dust.

Cited by 10 publications

References 29 publications

Health effects of World Trade Center (WTC) Dust: An unprecedented disaster with inadequate risk management

Health effects of World Trade Center (WTC) Dust: An unprecedented disaster with inadequate risk management

Article Commentary: Lessons Learned from the September 11th Disaster: A State Health Agency Perspective

Accelerated Spirometric Decline in New York City Firefighters With α;1-Antitrypsin Deficiency

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