Asssessing the Disease Severity in Patiens with Covid19 by Comparing Cycle Threshold Value of Rtpcr and Severity Score of Chest CT scan In A Teritiary Care Hospital

Kumar, Avadhesh; Surekha, A; Devi, Anuradha; Nagajyothi, B.

doi:10.1016/j.ijmmb.2021.08.205

Cited by 1 publication

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“…Several studies showed a significant association between the CT severity score and clinical outcomes. Studies [ 22 , 23 , 24 , 25 , 26 , 28 , 33 , 34 , 38 , 40 , 41 , 42 ], found that the CT severity score is positively associated with mortality and morbidity rates (increased risk of mortality and morbidity), the need for mechanical ventilation and for emergency medical treatment, patient survival, inflammatory markers, endotracheal intubation, oxygen saturation and demand, respiratory rate, length of hospital stays (prolonged hospitalization, >21 days), increased risk of noninvasive positive-pressure ventilation (NIPPV) failure, ICU admission, vaccination status, age, gender, co-morbidities, and stage of disease in the cohort of COVID-19 patients. It has also been found that CT severity score is higher in patients with severe COVID-19 pneumonia compared to those with mild or moderate disease.…”

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confidence: 99%

A Systematic Review of the Relationship between Chest CT Severity Score and Laboratory Findings and Clinical Parameters in COVID-19 Pneumonia

Majrashi,

Alhulaibi,

Nammazi

et al. 2023

Diagnostics

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The COVID-19 virus has infected millions of people and became a global pandemic in 2020. The efficacy of laboratory and clinical parameters in the diagnosis and monitoring of COVID-19 has been established. The CT scan has been identified as a crucial tool in the prognostication of COVID-19 pneumonia. Moreover, it has been proposed that the CT severity score can be utilized for the diagnosis and prognostication of COVID-19 disease severity and exhibits a correlation with laboratory findings such as inflammatory markers, blood glucose levels, and clinical parameters such as endotracheal intubation, oxygen saturation, mortality, and hospital admissions. Nevertheless, the correlation between the CT severity score and clinical or laboratory parameters has not been firmly established. The objective of this study is to provide a comprehensive review of the aforementioned association. This review used a systematic approach to collate and assess the existing literature that investigates the correlation between CT severity score and laboratory and clinical parameters. The search was conducted using Embase Ovid, MEDLINE Ovid, and PubMed databases, covering the period from inception to 20 May 2023. This review identified 20 studies involving more than 8000 participants of varying designs. The findings showed that the CT severity score is positively associated with laboratory and clinical parameters in COVID-19 patients. The findings indicate that the CT severity score exhibits a satisfactory level of prognostic accuracy in predicting mortality among patients with COVID-19.

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