Associations With Contralateral Recurrence Following Nephrectomy for Renal Cell Carcinoma Using a Cohort of 2,352 Patients

Bani-Hani, Ahmad H.; Leibovich, Bradley C.; Lohse, Christine M.; Cheville, John C.; Zincke, Horst; Blute, Michael L.

doi:10.1097/01.ju.0000148951.71353.8b

Cited by 52 publications

(35 citation statements)

References 13 publications

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“…11 In addition, we did not have any contralateral recurrence, a fact that may be secondary to absence of positive margins and low incidence of multifocal tumors. As reported by Bani-Hani et al, 12 these two factors are risk factors for contralateral recurrence for clear-cell renal cell carcinoma while nuclear grade was a significant predictor of contralateral recurrence for papillary renal cell carcinoma.…”

Section: Discussionmentioning

confidence: 52%

Oncological Outcomes of Laparoscopic Radical Nephrectomy for Renal Cancer

Colombo

Haber

Aron

et al. 2007

Clinics

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PURPOSE:To report the 5-year oncological outcomes of patients undergoing laparoscopic radical nephrectomy for renal cancer compared to a cohort of patients undergoing open radical nephrectomy. METHODS:We retrospectively analyzed the data of 88 patients undergoing radical nephrectomy for renal cell carcinoma prior to January 2000. Of these, 45 patients underwent laparoscopic radical nephrectomy, and 43 patients underwent open radical nephrectomy. Inclusion criteria comprised clinically organ-confined tumors of 15 cm or less in size without concomitant lymphadenopathy or vena cava thrombus. Oncological follow-up data were obtained from charts, radiological reports, and phone calls to patients or their families, and were calculated from the date of surgery to the date of last appointment with physician or date of death. RESULTS: All laparoscopic procedures were completed without open conversion. On comparing the laparoscopic radical nephrectomy and open radical nephrectomy groups, mean tumor size was 5.8 vs 6.2 cm (P = .44), mean blood loss was 183 vs 461 mL (P = .004), and mean operative time was 2.8 vs 3.7 hrs (P < .001). Over a mean follow-up of 5 years in the laparoscopic radical nephrectomy group and 6 years in the open radical nephrectomy group, the overall survival was 81% vs 79% (P = .47), and cancer-specific survival was 90% vs 92% (P = .70), respectively. CONCLUSIONS: Laparoscopic radical nephrectomy for renal cancer confers equivalent 5-year oncological outcomes to those of open surgery.

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Section: Discussionmentioning

confidence: 52%

Oncological Outcomes of Laparoscopic Radical Nephrectomy for Renal Cancer

Colombo

Haber

Aron

et al. 2007

Clinics

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“…The rarity of this case is supported in the literature. 1,8,13 This case underscores the need for judicious follow-up of the abdomen. We have found ultrasound easily accessible and relatively non-invasive in early detection even in remote area hospitals.…”

Section: Discussionmentioning

confidence: 99%

“…13 Positive surgical margins and multifocality were good predictors in clear cell RCC and nuclear grade for recurrent papillary RCC. 13 The patient in case 1 had a 5-cm tumour, of cystic clear cell variety, with margins negative and no multifocality relapse in the solitary left kidney 13 years after the initial right nephrectomy. She is currently disease-free 4 years after the partial nephrectomy.…”

Section: Discussionmentioning

confidence: 99%

Recurrent renal cell cancer: 10 years or more after nephrectomy

Abara¹,

Chivulescu

Clerk

et al. 2013

CUAJ

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Localized renal cell carcinoma (RCC) responds well to surgery. Patients often question how long they have to be on surveillance after their surgery. Several follow-up patterns have been described in the literature. Until 2009, no published established Canadian guidelines existed to assist Canadian health-care practitioners in the surveillance of these patients. We present 3 cases of RCC that recurred 10 years or longer after the initial nephrectomy. These cases emphasize the need for careful long-term follow-up, as recommended in the Canadian Urological Association guidelines. We also discuss the optimism of prolonged disease survival in the era of novel therapeutic agents that target angiogenesis.

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“…5 Early diagnosis of local and contralateral kidney recurrence (incidence < 2%) is useful since the most effective treatment is surgical resection (level 3). [6][7][8] Recurrence in the kidney is associated with positive surgical margins, multifocality and grade. Tumours that develop in the contralateral kidney can be treated with nephron-sparing surgery when detected at a small size.…”

Section: Rationale For Surveillancementioning

confidence: 99%