Associations of radiological features in Mycoplasma pneumoniae pneumonia

Guo, Qi; Li, Haiyan; Zhong, Yiping; Li, Ming; Chen, Xiaoke; Peng, Hong-lin; Yu, Hai-Qiong; Liu, Liang; Zhao, Qing-zhou; Jiang, Mei

doi:10.5114/aoms.2014.44863

Cited by 10 publications

(20 citation statements)

References 22 publications

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“…In previous non-ICU studies, compared to bacterial pneumonia, AP was associated with younger age and fewer comorbidities, a lower risk of severe respiratory failure, and better outcome [4,6,13,14,18]. For patients admitted to ICU, studies remained rare.…”

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confidence: 99%

Severe atypical pneumonia in critically ill patients: a retrospective multicenter study

Valade

Biard

Lemiale

et al. 2018

Ann. Intensive Care

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BackgroundChlamydophila pneumoniae (CP) and Mycoplasma pneumoniae (MP) patients could require intensive care unit (ICU) admission for acute respiratory failure. MethodsAdults admitted between 2000 and 2015 to 20 French ICUs with proven atypical pneumonia were retrospectively described. Patients with MP were compared to Streptococcus pneumoniae (SP) pneumonia patients admitted to ICUs. ResultsA total of 104 patients were included, 71 men and 33 women, with a median age of 56 [44–67] years. MP was the causative agent for 76 (73%) patients and CP for 28 (27%) patients. Co-infection was documented for 18 patients (viruses for 8 [47%] patients). Median number of involved quadrants on chest X-ray was 2 [1–4], with alveolar opacities (n = 61, 75%), interstitial opacities (n = 32, 40%). Extra-pulmonary manifestations were present in 34 (33%) patients. Mechanical ventilation was required for 75 (72%) patients and vasopressors for 41 (39%) patients. ICU length of stay was 16.5 [9.5–30.5] days, and 11 (11%) patients died in the ICU. Compared with SP patients, MP patients had more extensive interstitial pneumonia, fewer pleural effusion, and a lower mortality rate [6 (8%) vs. 17 (22%), p = 0.013]. According MCA analysis, some characteristics at admission could discriminate MP and SP. MP was more often associated with hemolytic anemia, abdominal manifestations, and extensive chest radiograph abnormalities. SP-P was associated with shock, confusion, focal crackles, and focal consolidation.ConclusionIn this descriptive study of atypical bacterial pneumonia requiring ICU admission, mortality was 11%. The comparison with SP pneumonia identified clinical, laboratory, and radiographic features that may suggest MP or CP pneumonia.Electronic supplementary materialThe online version of this article (10.1186/s13613-018-0429-z) contains supplementary material, which is available to authorized users.

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confidence: 99%

Severe atypical pneumonia in critically ill patients: a retrospective multicenter study

Valade

Biard

Lemiale

et al. 2018

Ann. Intensive Care

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“…Recently published studies [8,[10][11][12][13][14] have shown an increasing lobar pneumonia pattern. This study also confirmed the lobar pneumonia pattern in about a quarter of all MP patients, also reporting on the consolidation [10][11][12][13]16] in both lower lobes as the most common location.…”

Section: Discussionmentioning

confidence: 96%

“…In contrast, some reports showed that lobar pattern pneumonia accounts for about 33-38% [13,14], while other reports showed more localized consolidation, with most radiologic findings appearing as a lobar or segmental consolidation [15,16]. Recently published studies [8,[10][11][12][13][14] have shown an increasing lobar pneumonia pattern. This study also confirmed the lobar pneumonia pattern in about a quarter of all MP patients, also reporting on the consolidation [10][11][12][13]16] in both lower lobes as the most common location.…”

Section: Discussionmentioning

confidence: 99%

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Clinical features according to chest radiologic patterns ofMycoplasmapneumonia in children

Kim

et al. 2016

Yeungnam Univ J Med

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Background: Clinical differences in Mycoplasma pneumonia (MP) in children and adolescent patients according to abnormal infiltrate patterns on the chest X-ray were compared. Methods: From 2012 to 2015, patients (n=336) diagnosed with MP at Yeungnam University Medical Center have been classified as eiher lobar pneumonia or bronchopneumonia based on the infilterate patterns observed on chest X-ray. Cases were analyzed retrospectively for gender, age, seasonal incidence rate, main symptoms (fever duration, extrapulmonary symptoms), and laboratory results, including white blood cell count, hemoglobin, platelets, C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR), as well as concurrent respiratory virus infection. Results:The following results were observed. First, lobar pneumonia affected 22.0% of all MP patients and was the most common in preschool children, with a high incidence rate in November and December. Second, lobar pneumonia had a longer fever duration than bronchopneumonia (p<0.001), and also showed significantly higher platelets (336.8 vs. 299.1 k/µL, p=0.026), ESR (46.3 vs. 26.0 mm/hr, p<0.001) and CRP (4.86 vs. 2.18 mg/dL, p=0.001). Third, viral co-infection was more common in bronchopneumonia (p=0.017), affecting 66.7% of infants and toddlers (p=0.034). Finaly, lobar consolidation was most common in both lower lobes. Conclusion: MP in children has increased in younger age groups, and the rate of lobar pneumonia with severe clinical symptoms is higher in older children.

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“…We found that many clinical differences between two groups were similar to those described in other studies. [1314]…”

Section: Discussionmentioning

confidence: 99%

A preliminary study on the potential of Mycoplasma pneumoniae to induce dyskaryotic change in respiratory epithelium in adult community-acquired pneumonia

Yang

Luo

et al. 2016

J Res Med Sci

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Background:This study aimed to explore the cellular morphology of respiratory epithelium in Mycoplasma pneumonia (MpP) patients.Materials and Methods:The cast-off cell morphological findings from bronchoscopic brushings in MpP and community-acquired pneumonia (CAP) caused by typical pathogens were reviewed.Results:Compared with the CAP group, cellular dysplasia in respiratory tract epithelial brushings was significantly greater in MpP patients (P = 0.033).Conclusion:Unique biological characteristics and mechanisms of pathogenesis of Mycoplasma pneumoniae (Mp) may result in dyskaryotic changes in respiratory epithelium in adult MpP.

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Associations of radiological features in Mycoplasma pneumoniae pneumonia

Cited by 10 publications

References 22 publications

Severe atypical pneumonia in critically ill patients: a retrospective multicenter study

Severe atypical pneumonia in critically ill patients: a retrospective multicenter study

Clinical features according to chest radiologic patterns ofMycoplasmapneumonia in children

A preliminary study on the potential of Mycoplasma pneumoniae to induce dyskaryotic change in respiratory epithelium in adult community-acquired pneumonia

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