2001
DOI: 10.5271/sjweh.633
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Associations of lead biomarkers and delta-aminolevulinic acid dehydratase and vitamin D receptor genotypes with hematopoietic outcomes in Korean lead workers

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Cited by 20 publications
(14 citation statements)
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“…These results also agree with previous studies that reported that PbB levels higher than 25.0 mg/dl affected d-ALAD activity. 87,88 Similar results were obtained in studies correlating an increase in plasmatic and urinary d-ALA with PbB levels, [89][90][91] suggesting that d-ALAD activity is not a sensitive indicator of low Pb exposure. One important aspect of the d-ALAD biomarker that arises from the present study is the reduction in d-ALAD activity inhibition (61.59 + 1.15 U/L) from the value obtained by Hansen et al 24 of 38.80 + 1.10 U/L, a finding that is closely related to the decrease in PbB levels reported here compared to those obtained in that study.…”
Section: Discussionsupporting
confidence: 90%
“…These results also agree with previous studies that reported that PbB levels higher than 25.0 mg/dl affected d-ALAD activity. 87,88 Similar results were obtained in studies correlating an increase in plasmatic and urinary d-ALA with PbB levels, [89][90][91] suggesting that d-ALAD activity is not a sensitive indicator of low Pb exposure. One important aspect of the d-ALAD biomarker that arises from the present study is the reduction in d-ALAD activity inhibition (61.59 + 1.15 U/L) from the value obtained by Hansen et al 24 of 38.80 + 1.10 U/L, a finding that is closely related to the decrease in PbB levels reported here compared to those obtained in that study.…”
Section: Discussionsupporting
confidence: 90%
“…The obtained results confirmed a high positive correlation between the concentration of lead in the blood and urine, and years of service of the exposed subjects (r = 0.854, p < 0.01, and r = 0.722, p < 0.01, respectively). Lee et al found a high positive correlation between blood lead levels and years of service [25], which complies with the results obtained in the present research.…”
Section: Discussionsupporting
confidence: 82%
“…Pb concentration in the blood of the rats continuously intoxicated with 500 mg Pb/l MoniuszkoJakoniuk et al, 2003) is within a range of values noted in Pb workers (Lee et al, 2001). The blood Pb concentration, being the major indicator of exposure to this toxic metal, in the Pb and Pb + EtOH groups was 507.6 ± 28.8 and 801.7 ± 30.4 g/l, respectively.…”
Section: Animals and Experimental Protocolmentioning
confidence: 85%