Associations of foot ulceration with quality of life and psychosocial determinants among patients with diabetes; a case‐control study

Alosaimi, Fahad D.; Labani, Reem; Almasoud, Nouf; Alhelali, Nora; Althawadi, Lamya; AlJahani, Dhaherah Mani

doi:10.1186/s13047-019-0367-5

Cited by 16 publications

(13 citation statements)

References 50 publications

(76 reference statements)

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“…Despite efforts to reduce this disease menace in African countries, global projections have shown that the Africa continent will experience the most significant future increase in the burden of DM of about 156% by 2045 (Federation, 2017). Many studies have demonstrated that most individuals affected with diabetes experience higher anxiety, depression, and frustration than ordinary people (Alosaimi et al, 2019). Among these disorders, depression has been reported as the second mental disorder globally.…”

Section: Introductionmentioning

confidence: 99%

Meta-analysis of studies on depression prevalence among diabetes mellitus patients in Africa

Ogunsakin

Olugbara²,

Moyo³

et al. 2021

Heliyon

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Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion or insulin action. It can be caused by the consumption of carbohydrate meals or medication side effects. Depression as a comorbid condition in an individual with diabetes is accountable for increased disability, mortality, and significant health problem in patients. As a continent, Africa does not have an overall estimation of depression prevalence among diabetes mellitus patients at a regional level. Consequently, this study's purpose was to use the meta-analysis method to summarize estimates of extant studies that have reported depression prevalence among patients with diabetes mellitus in Africa. The literature search method was executed to classify studies with reported depression prevalence with evidently designed inclusion and exclusion criteria. In total, 20 studies from sundry screened articles were appropriate for ultimate inclusion in the meta-analysis. Since substantial heterogeneity was expected, a random-effects meta-analysis was carried out using the number of cases with a total sample size to estimate the prevalence of diabetes mellitus at a regional level. The residual amount of heterogeneity was found to be high according to the statistics of τ 2 ¼ 0.06; I 2 ¼ 99.10%, chi-square ¼ 2184.85, degree of freedom ¼ 19 and P ¼< 0.001. The pooled depression prevalence was 40% within a 95% confidence interval of 29%-51%. The meta-regression analysis result showed that none of the included moderators contributed to the heterogeneity of studies. The result of effect size estimates against its standard error showed publication bias with a P-value of 0.001. The meta-analysis findings of this study have indicated that depression prevalence in Africa is still high. Reporting on numerous risk factors like socio-demographic characteristics were not possible in this study because of a lack of completeness in the included articles. Consequently, screening diabetes patients for comorbid depression with its associated risk factors is highly recommended.

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Section: Introductionmentioning

confidence: 99%

Meta-analysis of studies on depression prevalence among diabetes mellitus patients in Africa

Ogunsakin

Olugbara²,

Moyo³

et al. 2021

Heliyon

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“…Studies on the prevalence and effect of pain on the quality of life in diabetic foot syndrome (DFS) patients showed results that most often refer to patients with neuropathic pain 16 and/or coexisting foot ulceration, 17 however, there are no studies on the influence of pain on the quality of life in patients with diabetes and post-amputation diabetic foot syndrome.…”

Section: Discussionmentioning

confidence: 99%

“…Also a question related to the assessment of the incidence of pain in the postoperative wound and/or the residual limb was asked. Pain intensity measurements were taken at baseline for all patients 7 days, 6 months and 12 months after surgery using a 10 cm VAS, 17 , 18 , 19 where 0 indicates no pain and 10 corresponds to the worst pain imaginable - the measurement was always performed by the researcher or a person trained by him.…”

Section: Methodsmentioning

confidence: 99%

Influence of Pain on the Quality of Life and Disease Acceptance in Patients with Complicated Diabetic Foot Syndrome

Krzemińska¹,

Kostka²

2021

DMSO

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The aim of the study was to evaluate the relationship between pain and quality of life and illness acceptance, anxiety and depression in a group of patients with complicated diabetic foot syndrome, following lower limb amputation. Patients and Methods: The studies were carried out in three stages: 7 days, 6 months and 12 months after surgery in a group of 100 patients after amputation of the lower limb due to complications resulting from type 2 diabetes. The study was performed using standardised instruments: WHOQOL-BREF, the Acceptance of Illness Scale (AIS), the Hospital Anxiety and Depression Scale (HADS), and the Visual Analog Scale (VAS) for pain intensity assessment. Results: Pain occurred in the examined patients throughout the study. The greatest intensity of pain was observed in the postoperative period and significantly weakened over time. Pain intensity was significantly associated with worse overall QoL perceived (−0.255, p=0.011/-0.283, p=0.005) and QoL scores in the physical and psychological domains at the first and second stage of the study (physical domains −0.257, p=0.011/-0.219, p=0.03 and psychological −0.22, p=0.029/-0.24/0.018). The intensity of pain negatively correlates with the acceptance of the disease in all three stages of the study, the greater the severity of pain, the lower the acceptance of illness (−0.298, p=0.003/-0.326, p=0.001/-0.26, p=0.009). The occurrence of anxiety and depression is highly dependent on the severity of pain, especially at the first and second stage of the study (anxiety 0.203, p=0.045/0.257, p=0.01, depression 0.299, p=0.003/0.253, p=0.012). The stronger the pain, the greater the severity of mood disorders. Conclusion: Pain and its severity are associated with QoL in the patients with complicated diabetic foot syndrome following lower limb amputation. Disease acceptance was lower in patients experiencing more severe pain at all stages of the study. There is an association of pain with the occurrence of anxiety and depression in amputees, especially 6 months after surgery.

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“…Nevertheless, the severity of somatic symptoms in the current study was very similar to that for Saudi patients with diabetes. 45 …”

Section: Discussionmentioning

confidence: 99%

“…However, psychosocial disorders, especially depressive and anxiety symptoms, were associated with poor QoL among patients with diabetes, skin disease, and sickle cell disease. 45 - 47 …”

Section: Discussionmentioning

confidence: 99%

Psychosocial predictors of quality of life among chronic hemodialysis patients

Alosaimi

Alshahrani

Aladhayani

et al. 2020

SMJ

Self Cite

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Objectives: To examine the association of several psychosocial disorders with quality of life (QoL) among chronic hemodialysis patients. Methods: A cross-sectional observational study was conducted in 2018 and recruited chronic hemodialysis patients from 3 major hemodialysis centers in Riyadh, Kingdom of Saudi Arabia (KSA). Quality of life was assessed using a previously validated Arabic version of the dialysis version-III of the QoL index. Results: A total of 101 patients (56 males and 45 females) were included. The mean age was 54.0±12.3 years. The overall mean of QoL was 88.8/100 points (out of 100). The family (95.0%) and psychological/spiritual (94.7%) domains had the highest scores. The prevalence of psychosocial disorders was 24.8% for depressive symptoms, 15.8% for anxiety symptoms, 88.1% for cognitive impairment, 76.8% for insecure attachment style, and 38.6% for medium/high severity of somatic symptoms. All psychosocial disorders and higher cognition level were negatively correlated with QoL (Spearman correlation r ranged between -0.228- -0.468). After adjusting for sociodemographic and clinical characteristics, anxiety symptoms and higher cognition level were independent predictors of poor QoL, while marital status (married) was an independent predictor of good QoL. Conclusion: We report higher QoL and relatively better psychosocial profiles among current chronic hemodialysis patients than reported before. Psychosocial disorders specially anxiety can negatively impact QoL. Patients who were not cognitively impaired were more negatively affected in QOL. The findings re-emphasize the importance of the early detection and management of psychosocial disorders to improve QoL in chronic hemodialysis patients.

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Associations of foot ulceration with quality of life and psychosocial determinants among patients with diabetes; a case‐control study

Cited by 16 publications

References 50 publications

Meta-analysis of studies on depression prevalence among diabetes mellitus patients in Africa

Meta-analysis of studies on depression prevalence among diabetes mellitus patients in Africa

Influence of Pain on the Quality of Life and Disease Acceptance in Patients with Complicated Diabetic Foot Syndrome

Psychosocial predictors of quality of life among chronic hemodialysis patients

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