Associations of Calcium and Magnesium in Serum and Hair with Bone Mineral Density in Premenopausal Women

Song, Chan Hee; Barrett‐Connor, Elizabeth; Chung, Jin-Woong; Kim, Sung Hyun; Kim, Kyung Soo

doi:10.1007/s12011-007-0011-2

Cited by 37 publications

(22 citation statements)

References 28 publications

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“…In a previous study, we could observe different [31] whereas dietary Mg reduction-induced bone loss with decreased serum Mg and elevated serum Ca levels in an animal study [32]. These results suggest that Ca and Mg have a cellular antagonism [33] and that balancing Ca and Mg is important to maintain optimal bone density.…”

Section: Discussionmentioning

confidence: 70%

Associations of Serum Ca and Mg Levels with Mental Health in Adult Women Without Psychiatric Disorders

Jung

Ock

Chung

et al. 2009

Biol Trace Elem Res

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Several lines of evidence from previous studies suggest that Calcium (Ca) and Magnesium (Mg) may be involved in intracellular and interneuronal processes associated with affective disorders. However, there have been inconsistent results on the effect of Ca and Mg on depressive mood disorder. This cross-sectional study was conducted to determine whether serum Ca and Mg levels, as well as serum Ca/Mg ratio, are associated with mental health in relatively healthy, adult women without psychiatric disorders. One hundred and twelve adult women were recruited from the outpatient clinic in a university hospital setting. Serum Ca and Mg levels were measured and indicators of mental health such as depression, anxiety, and stress were evaluated using two validated questionnaires; the Hospital Anxiety Depression Scale and the Modified Brief Encounter Psychosocial Instrument Stress Scale. After categorizing the serum Ca and Mg levels, and the Ca/Mg ratio into tertiles, the mean scores on each mental health scale were compared using analysis of covariance. The risk of depressive mood disorder according to the tertiles of serum Mg level and serum Ca/Mg ratio was assessed using logistic regression analysis. Women in the middle tertile of serum Ca/Mg ratio had significantly lower scores on depression and stress scales (p = 0.004 and p = 0.007, respectively) and a lower odds ratio (OR) for the risk of depressive mood disorder (OR = 0.31, CI(95%) 0.10-0.93) than those in the highest tertile. The OR for the risk of depressive mood disorder was higher in women in the lowest tertile of serum Mg than in those in the highest tertile (OR = 3.92, CI(95%) 1.11-13.83). Serum Mg level and serum Ca/Mg ratio may be involved in the mechanism for the progression of depressive mood or stress perception in relatively healthy, adult women.

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Section: Discussionmentioning

confidence: 70%

Associations of Serum Ca and Mg Levels with Mental Health in Adult Women Without Psychiatric Disorders

Jung

Ock

Chung

et al. 2009

Biol Trace Elem Res

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“…[30] But another recent research reported hair calcium level is negative associated with BMD and calcium intake. [18] In our study, BMD, calcium intake and hair calcium level have no significant relationship.…”

Section: Discussionmentioning

confidence: 99%

Coronary Calcification Is Reversely Related with Bone and Hair Calcium: The Relationship among Different Calcium Pools in Body

et al. 2016

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BackgroundWith aging, calcium efflux from bone is increased with age-related bone loss, and it can reduce bone mineral density (BMD). On the contrary, age-related calcium adoption into arterial wall progressively stiffens blood vessels. Theses process insinuates shift of calcium among different pools in body. However, their relationships have not been elucidated yet. So we investigated the correlation among calcium contents in different body pools, such as hair, bone, and blood vessels in women.MethodsWe analyzed 50 females retrospectively who measured Agatston coronary artery calcium score (CACS), BMD, and hair calcium concentration at a regular health check-up in a university hospital. CACS was achieved by coronary multidetector computed tomography, BMD was measured by dual energy X-ray absorptiometry in the lumbar spine and femur, and hair calcium level was checked by hair tissue mineral analysis.ResultsCACS inversely correlated with BMD (r=-0.280, P=0.049 with lumbar vertebrae 1-4, r=-0.310, P=0.028 with femur neck, r=-0.333, P=0.018 with femur total) and hair calcium concentration (r=-0.352, P=0.012).ConclusionsCACS has negative correlation with BMD and hair calcium level in women. Different body calcium pools such as bone, hair and blood vessel significantly correlated each other.

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“…A positive relationship between bone mass and dietary magnesium intake was found in young women [123][124][125][126][127], although results are not consistent across all skeletal sites. In postmenopausal women and older men, positive correlations between BMD and magnesium intake have been found although results are not consistent based on gender and race [128][129][130].…”

Section: Magnesiummentioning

confidence: 79%

Alternative Therapy through Nutrients and Nutraceuticals

Nieves

2013

Osteoporosis

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Associations of Calcium and Magnesium in Serum and Hair with Bone Mineral Density in Premenopausal Women

Abstract: Magnesium in serum and hair was associated with BMD in premenopausal women. The ratio of serum calcium to magnesium appears to be a significant indicator of BMD.

Cited by 37 publications

References 28 publications

Associations of Serum Ca and Mg Levels with Mental Health in Adult Women Without Psychiatric Disorders

Associations of Serum Ca and Mg Levels with Mental Health in Adult Women Without Psychiatric Disorders

Coronary Calcification Is Reversely Related with Bone and Hair Calcium: The Relationship among Different Calcium Pools in Body

Alternative Therapy through Nutrients and Nutraceuticals

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