“…HIV/STI risk in JIYA is further exacerbated by substance use and disorder (SU/D) among this population. A substantial body of literature documents the positive association between substance use (SU) and sexual risk behavior among adolescents and young adults (Bryan, Schmiege, & Magnan, 2012 ; Shorey et al, 2019 ; Tucker, Shih, Pedersen, Seelam, & D’Amico, 2019 ), including reduced engagement in, and adherence to, HIV care (Lucas, 2011 ). For example, among youth and adults who are HIV+, early onset and problem SU are associated with poor adherence to HIV medications, suboptimal viral load suppression (Arnsten et al, 2002 ; Comulada, Swendeman, Rotheram-Borus, Mattes, & Weiss, 2003 ; Cook et al, 2001 ; Gordillo, del Amo, Soriano, & González-Lahoz, 1999 ; Hosek, Harper, & Domanico, 2005 ) and difficulty accessing and remaining in HIV care (Bartlett, 2002 ; Freudenberg, 2006 ; Rich et al, 2001 ; Zaller et al, 2008 ).…”