Associations of aerobic and strength exercise with clinical laboratory test values

Abstract

ObjectivesPhysical exercise may affect levels of blood-based biomarkers. However, exercise status is seldom considered in the interpretation of laboratory results. This study reports the associations between habitual exercise participation and clinical laboratory test results.MethodsThe effects of days per week of aerobic and strength exercise participation on laboratory test results for 26 biomarkers in young adults aged 18 to 34 years (n = 80,111) were evaluated using percentile distribution analyses and multivariate regression.ResultsIn both men and women, more days per week of either aerobic or strength exercise were significantly associated with lower levels of glucose, hemoglobin A1c, LDL cholesterol, total cholesterol, triglycerides, estimated glomerular filtration rate, globulin, and C-reactive protein, and significantly higher levels of HDL cholesterol, creatinine, iron, and percent saturation (all p < .05). Type of exercise or gender influenced the observed relationships with exercise frequency for total cholesterol, aspartate aminotransferase, gamma-glutamyl transferase, alkaline phosphatase, uric acid, bilirubin, and iron binding capacity.ConclusionsPhysical exercise shifted the distribution of results into the direction suggestive of better health. Reported relationships may help clinicians and patients to better understand and interpret laboratory results in athletic populations and possibly re-evaluate interpretation of reference intervals for physically active populations.

Metabolic and Biomolecular Changes Induced by Incremental Long-Term Training in Young Thoroughbred Racehorses during First Workout Season

“…According to the literature, exercise has a powerful action on metabolism, which is influenced by the intensity and duration of the effort both in humans and racehorses [1][2][3][4][20][21][22][23]. Our results showed a significant and progressive decrease in glycaemia that remained within the RIs.…”

“…They show, for the first time in Thoroughbreds, a mild long-lasting increase in triglycerides during long-term, high-sprint-intensity training. Probably, as happens in endurance horses after long distances, TG play a crucial role in replenishing the intramuscular fat stores depleted in the course of repeated training sessions [3,23].…”

“…Lipolysis in muscle and adipose tissue, as well as hepatic synthesis of triglycerides are enhanced due to the increased oxidative capacity for fat utilization during training [21,22,25]. Lipolysis, other than glycogenolysis and gluconeogenesis, is assumed to be stimulated by catecholamines and other catabolic hormones related to stress (insulin and cortisol) and is thus reported to affect glucose and lipid metabolism and provoke an exercise-induced transient hyperlipemia [23,25]. Regarding Thoroughbreds, it has been demonstrated that racehorses reach higher levels of circulating TG (2× greater) and cholesterol (20%) at rest after 8 weeks of training compared with riding horses [23].…”

Responses of Uric Acid, Glucose, Thyroid Hormones and Liver Enzymes to Aerobic and Combined Exercises in University Students

“…In another study, it was found that an aerobic exercise program administered to elderly women at a intensity of 50-70% for 45 weeks to 8 weeks 3 days a week led to a decrease in uric acid level (Moghadam, 2015). In a study, it was emphasized that glucose and uric acid levels were lower in individuals who participated in aerobic or strength training (Fragala, Bi, Chaump, Kaufman, & Kroll, 2017). It was determined that aerobic exercises applied to elderly obese women for 60 minutes at a intensity of 50-80% 5 days a week for 8 weeks caused a decrease in glucose level (Park et al, 2019).…”

Effect of Compression Modalities for Recovery on Wrestlers Biomarkers in One Day Tournament

“…Analytic treatment of research data resulted differences among the four research groups, table (2) represents the means, LSD and enhancement percentage of the pre-tests of the research variables" Serum Creatinine SCR", "Lactic acid LA" and "Glucose GL" of the four research groups "control cont. ", " Experimental 1 Exp1", "Experimental 2 Exp2" and "Experimental 3 Exp3" (Fragala M., et al 2017) (24) Proven that strength exercise was associated with higher levels of creatinine, where physical performance compels athlete's muscles to process high amounts of creatine which produce higher levels of serum creatinine.…”