“…It is therefore important to investigate which are the factors driving benzodiazepine use. A paper in this issue investigates factors associated with later benzodiazepine use in adolescents (Kujala et al ., 2022). This is another clear example of interplay among clinical and environmental factors, as the results showed that several psychopathological and environmental variables contributed to later benzodiazepine use, with differences between males and females.…”