Associations between social determinants of health, perceived discrimination, and body mass index on symptoms of depression among young African American mothers

Millender, Eugenia; Barile, John P.; Bagneris, Jessica R; Harris, Rachel; Faria, Ludmila De; Wong, Frank; Crusto, Cindy A.; Taylor, Jacquelyn Y.

doi:10.1016/j.apnu.2020.09.014

Cited by 19 publications

(14 citation statements)

References 42 publications

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“…Studies also focused on the social determinants of (mental) health; these are the conditions in which people are born, live, learn, work, play, and age, and have a significant influence on wellbeing [ 291 ]. Factors such as age, social or socioeconomic status, social support, financial strain and deprivation, food insecurity, education, employment status, living arrangements, marital status, race, childhood conflict and bullying, violent crime exposure, abuse, discrimination, (self)-stigma, ethnicity and migrant status, working conditions, adverse or significant life events, illiteracy or health literacy, environmental events, job strain, and the built environment have been linked to depression, among others [ 52 , 133 , 235 , 236 , 239 , 252 , 269 , 280 , 292 , 293 , 294 , 295 , 296 , 297 , 298 , 299 , 300 , 301 , 302 , 303 , 304 , 305 , 306 , 307 , 308 , 309 , 310 , 311 , 312 , 313 , 314 , 315 , 316 , 317 , 318 , 319 , 320 , 321 , 322 , 323 , 324 , 325 , 326 ,…”

Section: Resultsmentioning

confidence: 99%

Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature

2021

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Depression is one of the leading causes of disability, and, if left unmanaged, it can increase the risk for suicide. The evidence base on the determinants of depression is fragmented, which makes the interpretation of the results across studies difficult. The objective of this study is to conduct a thorough synthesis of the literature assessing the biological, psychological, and social determinants of depression in order to piece together the puzzle of the key factors that are related to this condition. Titles and abstracts published between 2017 and 2020 were identified in PubMed, as well as Medline, Scopus, and PsycInfo. Key words relating to biological, social, and psychological determinants as well as depression were applied to the databases, and the screening and data charting of the documents took place. We included 470 documents in this literature review. The findings showed that there are a plethora of risk and protective factors (relating to biological, psychological, and social determinants) that are related to depression; these determinants are interlinked and influence depression outcomes through a web of causation. In this paper, we describe and present the vast, fragmented, and complex literature related to this topic. This review may be used to guide practice, public health efforts, policy, and research related to mental health and, specifically, depression.

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Section: Resultsmentioning

confidence: 99%

Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature

2021

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“…Authors have begun to assert the outsized importance of SDOHs as the basis of many healthcare disparities previously ascribed solely to other variables such as race, sex, or income 28,29 . Although the analysis herein supports this notion, additional studies have emphasized the extent to which these same variables inform SDOHs 29–32 . These considerations suggest a more nuanced conclusion, in which variables including race, sex, and income form integral components of the SDOH in addition to other less-easily-categorizable variables such as nutrition security, inadequate housing, and illiteracy.…”

Section: Discussionmentioning

confidence: 73%

“…28,29 Although the analysis herein supports this notion, additional studies have emphasized the extent to which these same variables inform SDOHs. [29][30][31][32] These considerations suggest a more nuanced conclusion, in which variables including race, sex, and income form integral components of the SDOH in addition to other less-easily-categorizable variables such as nutrition security, inadequate housing, and illiteracy. These latter, poorly quantized variables highlight the importance of SDOH Z code usage by physicians and their subsequent analysis by investigators.…”

Section: Discussionmentioning

confidence: 99%

The Impact of Social Determinants of Health on Pressure Injury Progression: A Retrospective Chart and Scoping Review

Sasson

Duan²,

Patel³

et al. 2023

Adv Skin Wound Care

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OBJECTIVE:To understand the effects of nutrition security and social determinants of health (SDOHs) on pressure injury (PI) progression through a scoping review and retrospective review of patients reporting to New England's largest healthcare system. METHODS:Authors performed a scoping review for full-text, original articles reporting outcomes data specific to PIs in patients with socially informed nutrition insecurity. Investigators also performed a retrospective review of all patients from 2012 to 2021 to search for patients with PI documentation and International Classification of Diseases, Tenth Revision Z codes related to the SDOHs. RESULTS:A full-text review of 2,323 articles from 1965 to 2020 failed to locate any eligible studies. Investigators identified 1,044 patients who met the inclusion criteria; 50.7% were men, 74.3% were White, and 13.3% had evidence of detrimental SDOHs. The average PI duration was 12.13 days (interquartile range, 6 days). Multivariate regression analysis revealed that PI duration was longer in men, Black patients, and patients with evidence of detrimental SDOHs compared with their converse counterparts ( P < .0001). The presence of detrimental SDOHs independently predicted an increased duration of disease by 13.07 days (95% CI, 8.99-17.15; t = 6.29, P < .0001).CONCLUSIONS: A patient's SDOH history has a significant and considerably stronger correlation with disease progression than predictors that are traditionally studied such as sex, race, or body mass index. These findings are novel, as highlighted by the absence of data uncovered in the literature. These data carry relevance for plastic surgeons wishing to prevent early recurrence following operative closure of PI-related wounds.

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“…Mounting evidence confirms the damaging effects of perceived discrimination and other components of racism on health, 63,64 particularly CM health in AAW. 65-67 In line with the notion of biological weathering 68,69 —described as the early deterioration of health as a physiologic result of socioeconomic disadvantage—several studies show associations between measures of racial discrimination and socioeconomic stress with accelerated aging and DNA methylation among AAW. 70-73 Further, experiences of discrimination may also affect children of AAW, through effects on parenting stress, highlighting the intergenerational impact of discrimination on health.…”

Section: Discussionmentioning

confidence: 89%

Associations Between DNA Methylation Age Acceleration, Depressive Symptoms, and Cardiometabolic Traits in African American Mothers From the InterGEN Study

Perez

Vorderstrasse

et al. 2022

Genet Epigenet

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Background: African American women (AAW) have a high risk of both cardiometabolic (CM) illness and depressive symptoms. Depressive symptoms co-occur in individuals with CM illness at higher rates than the general population, and accelerated aging may explain this. In this secondary analysis, we examined associations between age acceleration; depressive symptoms; and CM traits (hypertension, diabetes mellitus [DM], and obesity) in a cohort of AAW. Methods: Genomic and clinical data from the InterGEN cohort (n = 227) were used. Age acceleration was based on the Horvath method of DNA methylation (DNAm) age estimation. Accordingly, DNAm age acceleration (DNAm AA) was defined as the residuals from a linear regression of DNAm age on chronological age. Spearman’s correlations, linear and logistic regression examined associations between DNAm AA, depressive symptoms, and CM traits. Results: DNAm AA did not associate with total depressive symptom scores. DNAm AA correlated with specific symptoms including self-disgust/self-hate (−0.13, 95% CI −0.26, −0.01); difficulty with making decisions (−0.15, 95% CI −0.28, −0.02); and worry over physical health (0.15, 95% CI 0.02, 0.28), but were not statistically significant after multiple comparison correction. DNAm AA associated with obesity (0.08, 95% CI 1.02, 1.16), hypertension (0.08, 95% CI 1.01, 1.17), and DM (0.20, 95% CI 1.09, 1.40), after adjustment for potential confounders. Conclusions: Associations between age acceleration and depressive symptoms may be highly nuanced and dependent on study design contexts. Factors other than age acceleration may explain the connection between depressive symptoms and CM traits. AAW with CM traits may be at increased risk of accelerated aging.

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Associations between social determinants of health, perceived discrimination, and body mass index on symptoms of depression among young African American mothers

Cited by 19 publications

References 42 publications

Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature

Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature

The Impact of Social Determinants of Health on Pressure Injury Progression: A Retrospective Chart and Scoping Review

Associations Between DNA Methylation Age Acceleration, Depressive Symptoms, and Cardiometabolic Traits in African American Mothers From the InterGEN Study

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