Associations between postnatal weight gain, change in postnatal pulmonary function, formula feeding and early asthma

Turner, Steve; Zhang, Guicheng; Young, Sally; Cox, M.; Goldblatt, Jack; Landau, Lou; Souëf, Peter Le

doi:10.1136/thx.2006.064642

Cited by 68 publications

(85 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies conducted in different populations have shown an effect of weight gain during infancy on pulmonary function in early (10,25) or late (9) life. A prospective study conducted in Australia concluded that fast weight gain between the first and the twelfth months of life, particularly in children of low birth weight, was associated with decreased pulmonary function at 12 months and increased symptoms of transient asthma, suggesting an important association between somatic growth and pulmonary function in childhood (25) .…”

Section: Discussionmentioning

confidence: 99%

“…A prospective study conducted in Australia concluded that fast weight gain between the first and the twelfth months of life, particularly in children of low birth weight, was associated with decreased pulmonary function at 12 months and increased symptoms of transient asthma, suggesting an important association between somatic growth and pulmonary function in childhood (25) . Likewise, Lucas et al reported that when weight gain and pulmonary function were evaluated between 5 and 14 weeks of life, higher rates of weight gain were positively associated with impaired pulmonary function (10) .…”

Section: Discussionmentioning

confidence: 99%

“…In early pregnancy, environmental factors may impair correct cell division in the airways, leading to abnormalities in programming pulmonary function (27) . Nevertheless, in some studies, low birth weight was not a prerequisite for the occurrence of fast growth and subsequent impaired pulmonary function (25) . Unfortunately, the effect of low birth weight could not be analysed in the current study sample due to the small number of children with this condition.…”

Section: Discussionmentioning

confidence: 99%

“…Unfortunately, the effect of low birth weight could not be analysed in the current study sample due to the small number of children with this condition. Another hypothesis is that children with normal birth weight and exposed to a hyperenergetic diet gain weight rapidly, but rapid growth is not accompanied by a parallel improvement in pulmonary function because of defective airways or air space development or the inability of airway growth to keep pace with somatic growth (25) . In the present study, conducted in the general population, there were only two children with abnormal lung function (FEV 1 :FVC ,80 %), limiting our capacity to Data are presented as number of cases (n) and prevalence (%).…”

Section: Discussionmentioning

confidence: 99%

“…Few studies have evaluated the association between somatic growth in early childhood and asthma or lung function at school age or in adulthood (7)(8)(9)(24)(25)(26) . Fast growth in early childhood was associated with wheezing (7,24) in scholars.…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Weight gain in the first two years of life, asthma and atopy: the SCAALA cohort study

Matos

Jesus

Saldiva³

et al. 2013

Public Health Nutr.

View full text Add to dashboard Cite

Objective: To evaluate the association between weight gain in the first two years of life and the occurrence of wheezing, asthma, serum IgE, skin reactivity and pulmonary function. Design: Cohort study. Setting: The metropolitan region of Salvador, Bahia, Brazil. Subjects: The association was studied between 1997 and 2005 in 669 children up to 11 years of age. Data were collected on asthma and risk factors, both current factors and those present in the first years of life. Weight gain was considered fast when the Z-score was .0?67. Poisson regression was used in the multivariate statistical analysis. Results: Wheezing was reported in 25?6 % of the children. Weight gain was considered fast (Z-score .0?67) in 29?6 % of the children and slow (Z-score ,20?67) in 13?9 %. Children in the slow weight gain group had 36 % fewer symptoms of asthma (prevalence ratio 5 0?65; 95 % CI 0?42, 0?99). Conclusions: Slower weight gain in the early years of life may constitute a protective factor against symptoms of asthma. The relevance of this finding for public health is not yet certain, since it is known that children with slow and fast weight gain may be more likely to develop adverse health consequences related to both these situations.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Weight gain in the first two years of life, asthma and atopy: the SCAALA cohort study

Matos

Jesus

Saldiva³

et al. 2013

Public Health Nutr.

View full text Add to dashboard Cite

show abstract

Prevalence and risk factors of wheeze in Dutch infants in their first year of life

Visser¹,

García‐Marcos²,

Eggink³

et al. 2010

Pediatric Pulmonology

View full text Add to dashboard Cite

Factors operating in the first year of life are critical in determining the onset and persistence of wheezing in preschool children. This study was designed to examine the prevalence and risk factors of wheeze in the first year of life in Dutch infants. This was a population-based survey of 13-month-old infants visiting well baby clinics for a scheduled immunization. Parents/caregivers completed a standardized validated questionnaire on respiratory symptoms in the first year of life and putative risk factors. The independent influence of these factors for wheeze was assessed by multiple logistic regression analysis. A total of 1,115 questionnaires were completed. Wheeze ever (with a prevalence in the first year of life of 28.5%) was independently associated with male gender, eczema, sibs with asthma, any allergic disease in the family, day care, damp housing, and asphyxia. Recurrent wheeze (prevalence 14.5%) showed independent associations with eczema, sibs with asthma, and day care. In addition to these factors, severe wheeze (prevalence 15.4%) was also associated with premature rupture of membranes during birth, and with damp housing. Wheeze is common during the first year of life, and places a major burden on families and the health care system. Factors associated with wheeze are mainly related to markers of atopic susceptibility, and to exposure to infections. The strongest modifiable risk factor for wheeze in the first year of life is home dampness. Interventions to reduce home dampness to reduce wheeze in infancy should be examined.

show abstract

Relation of early childhood growth and wheezing phenotypes to adult lung function

Sherrill¹,

Guerra²,

Wright³

et al. 2011

Pediatric Pulmonology

View full text Add to dashboard Cite

Summary Rationale Several studies have reported associations between indicators of birth size and postnatal growth rates with levels of pulmonary function achieved as adults. The objective of this study was to determine if levels and/or rates of weight gain, measured in early life (birth-6 yrs), are associated with FVC or FEV1 levels achieved in young adulthood and if these associations differ by early childhood wheezing phenotypes. Methods We used data from participants in the Tucson Children's Respiratory Study (CRS), a prospective birth cohort study. Weight was measured quarterly up to age 3 yrs and again at age 6 years. Pulmonary function was assessed at ages 16 and 22. Mean weight and slope of weight growth between 3 and 6 yrs were estimated using standardized residuals. Longitudinal models were used to determine predictors of FVC and FEV1 at ages 16 and 22 yrs. Results There were 127 non-Hispanic white subjects that had at least 4 weight measures and one or more pulmonary function measures as young adults. After adjusting for sex, height, and age, the standardized slope of weight growth, (between 3 and 6 years), was positively associated with higher levels of FVC at age 16 and 22 years (p=0.0001) among subjects who did not have pre-school wheezing. However, this association was completely absent among subjects who had wheezing lower respiratory tract illnesses in the first three years of life. Similar trends were found for FEV1. Conclusion The rate of weight gain between 3-6 yrs is significantly positively related to adult FVC and FEV1 and this association is modified by early wheezy phenotypes.

show abstract

Associations between postnatal weight gain, change in postnatal pulmonary function, formula feeding and early asthma

Cited by 68 publications

References 26 publications

Weight gain in the first two years of life, asthma and atopy: the SCAALA cohort study

Weight gain in the first two years of life, asthma and atopy: the SCAALA cohort study

Prevalence and risk factors of wheeze in Dutch infants in their first year of life

Relation of early childhood growth and wheezing phenotypes to adult lung function

Contact Info

Product

Resources

About