Associations between off-label feed additives and farm size, veterinary consultant use, and animal age

Dewey, Catherine E.; Cox, Barbara D.; Straw, Barbara E.; Bush, Eric J.; Hurd, H. Scott

doi:10.1016/s0167-5877(96)01077-x

Cited by 45 publications

(32 citation statements)

References 7 publications

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“…Based on interview with farmers, it is used as growth promoter for pigs in the farms. Other antibiotics such as sulfamonomethoxine, doxycycline, enrofloxacin, trimethoprim and florfenicol, which were detected in the feeds of farm S3, were used mainly for disease prevention and treatment according to the dose of these antibiotics in the feed samples (Dewey et al, 1997), although they are allowed to be used as feed additives (MOA, 2001). …”

Section: Use Of Antibiotics In the Livestock Farmsmentioning

confidence: 99%

Excretion masses and environmental occurrence of antibiotics in typical swine and dairy cattle farms in China

Zhou

Ying

Liu

et al. 2013

Science of The Total Environment

361

131

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Section: Use Of Antibiotics In the Livestock Farmsmentioning

confidence: 99%

Excretion masses and environmental occurrence of antibiotics in typical swine and dairy cattle farms in China

Zhou

Ying

Liu

et al. 2013

Science of The Total Environment

361

131

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“…Data about the use of feed additives in swine feeds from the United States National Swine Survey showed that up to 57% of 699 examined feeds used by the swine industry contain antibiotic levels three to four time higher than recommended levels (Dewey et al, 1997). Only a fraction of antibiotics fed to swine are metabolized by them, the nonmetabolized antibiotics or residues may remain unchanged through the animal digestion system and they are excreted in animal waste (Gustafson and Bowen, 1997;Onan and LaPara, 2003).…”

Section: Sub-therapeutic Usage Of Antibiotics In Swine Production Andmentioning

confidence: 99%

Occurrence of Tylosin-Resistant Enterococci in Swine Manure and Tile Drainage Systems under No-Till Management

Hoang

Soupir

Liu

et al. 2013

Water Air Soil Pollut

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“…Concerns about potential risks for human health due to the use and misuse of AB in animal feeds (Dewey et al, 1997) have led to their ban as growthpromoters throughout Europe since 1 January 2006 (Regulation (EC) No. 1831No.…”

Section: Introductionmentioning

confidence: 99%

“…/2003. Risks to human health include the possibility of AB residues in meat, unapparent carriage of anti-microbial drug-resistant bacteria, and exchange of plasmids from AB-resistant bacteria of swine to human pathogens making them resistant to AB (Dewey et al, 1997;Anadon and Martinez-Larranaga, 1999;Pugh, 2002). In-feed AB were used not only to improve growth but also to control enteric infections during critical periods such as weaning.…”

Section: Introductionmentioning

confidence: 99%

Natural alternatives to in-feed antibiotics in pig production: can immunomodulators play a role?

Gallois¹,

Rothkötter

Bailey

et al. 2009

Animal

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As a result of the European ban of in-feed growth-promoting antibiotics, new strategies are being developed to increase the resistance to disease in farm animals. In pig production, this is of particular importance during the weaning transition when piglets are subjected to major stressful events, making them highly sensitive to digestive disorders. At this time, the development of both innate and adaptive immunity at the mucosal surface is critical in preventing the potential harmful effects of intestinal pathogenic agents. Strategies aiming at stimulating natural host defences through the use of substances able to modulate immune functions have gained increasing interest in animal research, and different bioactive components a priori sharing those properties have been the subject of in vivo nutritional investigations in pig. Among these, yeast derivates (b-glucans and mannans) are able to interact with immune cells, particularly phagocytic cells. However, studies where they have been fed to pigs have shown inconsistent results, suggesting that their ability to target the sensitive immune cells through the oral route is questionable. The plant extracts, which would benefit from a positive image in the public opinion, have also been tested. However, due to a lack of data on the bioactive components of particular plants and the large diversity of species, it has proved difficult to prepare extracts of equivalent potency and thus, the literature on their influence on pig immunity remains inconclusive. In considering piglet immunity and health benefits, the most promising results to date have been obtained with spray-dried animal plasma, whose positive effects would be provided by specific antibodies and nonspecific competition of some plasma components with bacteria for intestinal receptors. The major positive effect of spray-dried animal plasma is in reducing the infiltration of gut-associated lymphoid tissue by immune cells, which is likely to be the result of a decreased colonisation by potentially harmful bacteria. This review also highlights the limitations of some of the published in vivo studies on the immunomodulatory activity of certain feed additives. Among those, the lack of standardisation of extracts and the heterogeneity of piglet-rearing conditions (e.g. exposure to pathogens) are likely the most limiting.

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Associations between off-label feed additives and farm size, veterinary consultant use, and animal age

Cited by 45 publications

References 7 publications

Excretion masses and environmental occurrence of antibiotics in typical swine and dairy cattle farms in China

Excretion masses and environmental occurrence of antibiotics in typical swine and dairy cattle farms in China

Occurrence of Tylosin-Resistant Enterococci in Swine Manure and Tile Drainage Systems under No-Till Management

Natural alternatives to in-feed antibiotics in pig production: can immunomodulators play a role?

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