Associations Between Nurse-Guided Variables and Plasma Oxytocin Trajectories in Premature Infants During Initial Hospitalization

Weber, Arthur L.; Harrison, Tondi M.; Sinnott, Loraine T.; Shoben, Abigail B.; Steward, Deborah K.

doi:10.1097/anc.0000000000000452

Cited by 10 publications

(16 citation statements)

References 99 publications

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“…Therefore, when infants experience reducedstress states, they are able to better engage with their caregivers to facilitate bonding and are better able to safely feed, and their gastrointestinal tracts function to support digestion, restoration, and growth. The release of oxytocin not only has these direct positive benefits but also acts to block activation of the HPA axis (Gimpl & Fahrenholz, 2001), resulting in protection from the negative effects of stress as well (Weber, Harrison, Sinnott, Shoben, & Steward, 2018).…”

Section: Physiologic Response To Low Levels Of Stressmentioning

confidence: 99%

“…Despite the evidence supporting SSC, data suggest that infants in the United States receive less than 1 hour of SSC per day and that this varies considerably, with some infants going weeks without any SSC (Reynolds et al, 2013;Weber, Harrison, Sinnott, et al, 2018). In multiple studies, researchers explored the facilitators and barriers to implementation of SSC in the NICU, and the results are fairly consistent across studies.…”

Section: Implications For Nursing Practicementioning

confidence: 99%

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Physiology of Stress and Use of Skin-to-Skin Care as a Stress-Reducing Intervention in the NICU

Pados¹

2019

Nursing for Women's Health

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Section: Physiologic Response To Low Levels Of Stressmentioning

confidence: 99%

Section: Implications For Nursing Practicementioning

confidence: 99%

Physiology of Stress and Use of Skin-to-Skin Care as a Stress-Reducing Intervention in the NICU

Pados¹

2019

Nursing for Women's Health

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“…Of these 19 studies, 10 (52.6%) evaluated only infants, 21-30 2 (10.5%) evaluated only parents, 31,32 and 7 (36.9%) evaluated both infants and parents. [33][34][35][36][37][38][39] For the purposes of this review, the findings from the infant (see Supplementary Table 1, available at: http://links.lww.com/ANC/A93) [21][22][23][24][25][26][27][28][29][30][33][34][35][36][37][38][39] and parent (see Supplementary Table 2, available at: http:// links.lww.com/ANC/A94) [31][32][33][34][35][36][37][38][39] studies are presented separately. Standardized criteria were developed to review the 2 groups of studies.…”

Section: What This Study Addsmentioning

confidence: 99%

A Systematic Review of the Effects of Skin-to-Skin Contact on Biomarkers of Stress in Preterm Infants and Parents

Forde

Fang

Miaskowski

2021

Advances in Neonatal Care

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Background: Premature infants and their parents experience significant stress related to separation and lifesaving procedures. While evidence suggests that skin-to-skin contact (SSC) is a stress-reducing intervention for both neonates and parents, the mechanisms that underlie its efficacy are not well understood. Objective: Purpose of this systematic review is to summarize the current state of knowledge on changes in biomarkers (ie, oxytocin [OT], cortisol, hypoxanthine, xanthine, uric acid, and allantoin), associated with SSC in premature infants and parents, that may reflect physiologic responses to stress. Methods: A comprehensive literature search was conducted from 1990 to 2020. Studies were selected using prespecified inclusion and exclusion criteria. Results: Of the 175 studies identified, only 19 are included in this review. Ten studies evaluated only infants, 2 evaluated only parents, and 7 evaluated for changes in biomarkers in both infants and parents. Cortisol was the most common biomarker evaluated. While changes in infants' cortisol levels were highly variable, in 55% of the parent studies, parent cortisol levels decreased following SSC. In both parents and infants, OT levels decreased following SSC. Only 1 study found that allantoin levels were significantly lower in infants who received SSC. Implications for Practice and Research: While evidence suggests the numerous benefits of SSC, additional research is needed to identify the optimal biomarker to determine the mechanisms that underlie these effects. The use of novel biomarkers (eg, gene expression changes microbiome) may provide new insights into the mechanisms that underlie the efficacy of SSC. Video Abstract available at: https://journals.lww.com/advancesinneonatalcare/Pages/videogallery.aspx?autoPlay=false&videoId=48

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“…The Italian Society of Neonatology guidelines endorsed by the Union of European Neonatal and Perinatal Societies (UENPS) suggest that rooming-in of mother and newborn is workable if a mother is SARS-CoV-2 positive or is a person under investigation (PUI), or is asymptomatic or has minimal symptoms at delivery, but with strict infection control measures 63 . Ample research-based evidence has concluded that early maternal-newborn bonding positively impacts the growth and development in term and pre-term neonates 64 , 65 . Early separation may negatively affect bonding, breast milk production and mental health of the mother during the hospital stay and after discharge with uncertain short- and long-term implications.…”

Section: Introductionmentioning

confidence: 99%

Changes in Clinical Care of the Newborn During COVID-19 Pandemic

Doctor

Kamat

Sood

2021

Pediatric Clinics of North America

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Coronavirus Disease of 2019 (COVID-19) has afflicted the health of women and children across all age groups. Since the outbreak of the pandemic in December 2019, various epidemiological, immunologic, clinical and pharmaceutical studies have been conducted across the world to understand its infectious characteristics, pathogenesis and clinical profile in affected individuals, with the hope of improving outcomes and ultimately leading to the development of vaccinations. COVID-19 has shown to affect pregnant women more seriously than non-pregnant women, endangering the health of the newborn. Various changes in the guidelines have been implemented in antenatal care of pregnant women, their delivery as well as newborn care during the COVID-19 pandemic, with the hope of reducing the risk of viral transmission and, in turn, improve outcomes in pregnant women and children. In this review, we highlight the current trends of clinical care in pregnant women and newborn during COVID 19 pandemic

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Associations Between Nurse-Guided Variables and Plasma Oxytocin Trajectories in Premature Infants During Initial Hospitalization

Abstract: Replication with larger sample sizes and randomized controlled trial designs is needed to test effects of specific nursing interventions on infant OT.

Cited by 10 publications

References 99 publications

Physiology of Stress and Use of Skin-to-Skin Care as a Stress-Reducing Intervention in the NICU

Physiology of Stress and Use of Skin-to-Skin Care as a Stress-Reducing Intervention in the NICU

A Systematic Review of the Effects of Skin-to-Skin Contact on Biomarkers of Stress in Preterm Infants and Parents

Changes in Clinical Care of the Newborn During COVID-19 Pandemic

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