Associations between Nicotine Metabolites and Serum Neurofilament Light Chain Levels in the General Population
Erhan Tang,
Qianqian Ji,
Yueting Liao
et al.
Abstract:Background: Nicotine has been recognized for enhancing cognitive functions, with serum neurofilament light chain (sNfL) as a biomarker for neurological conditions. However, the relationship between nicotine and its metabolites and sNfL levels remains underexplored. This study aims to investigate the associations of serum and urine levels of cotinine and trans-3’-hydroxycotinine (hydroxycotinine) with sNfL levels in a broad population.
Methods: Employing data from the National Health and Nutrition Examination S… Show more
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