Associations between migraine, celiac disease, non-celiac gluten sensitivity and activity of diamine oxidase

Histamine Intolerance: The Current State of the Art

“…Miyoshi et al demonstrated that DAO activity can be a useful predictor of intestinal mucosal damage in patients receiving chemotherapy [ 76 ]. Additionally, DAO deficiency has also been linked to certain functional gastrointestinal disorders, such as carbohydrate malabsorption and nonceliac gluten sensitivity (NCGS) [ 63 , 73 , 77 , 78 , 79 ]. Enko et al found that a concomitant reduction in DAO and lactase enzyme activities could be a consequence of mucosal damage in the small intestine due to gastrointestinal disorders (e.g., gastroenteritis, irritable bowel syndrome, short bowel syndrome and gastrointestinal surgery) [ 73 ].…”

“…More recently, two works have suggested a potential relationship between a reduced DAO activity and the presence of NCGS. Schnedl et al based this relationship on the broad parallelism between the symptomatology of NCGS and histamine intolerance, while the pilot study conducted by Griauzdaite et al reported a strong association between reduced DAO activity and the presence of NCGS, although with a reduced number of patients [ 77 , 78 ]. In fact, Griauzdaite et al found out that nine of 10 patients with NCGS had decreased serum DAO activity levels [ 78 ].…”

“…Schnedl et al based this relationship on the broad parallelism between the symptomatology of NCGS and histamine intolerance, while the pilot study conducted by Griauzdaite et al reported a strong association between reduced DAO activity and the presence of NCGS, although with a reduced number of patients [ 77 , 78 ]. In fact, Griauzdaite et al found out that nine of 10 patients with NCGS had decreased serum DAO activity levels [ 78 ]. This recently indicated relationship between both disorders, NCGS and histamine intolerance, should be further explored as it may be of interest for the correct clinical management of affected patients.…”

“…However, the prevalence of DAO deficiency in the control population amounted up to 44%, which was attributed to the fact that certain individuals could present other symptoms associated with histamine intolerance or DAO deficiency other than migraines. Another study with 44 migraine patients reported a 60% prevalence of DAO deficiency and a significant copresence of certain gastrointestinal disorders, such as celiac disease and NCGS [ 78 ].…”

Parasitas Com Potencial Patogênico Ao Homem Em Rúcula (Eruca Sativa) Comercializadas Em Cascavel, Paraná

“…Os pricipais assuntos delimitantes na escolha dos artigos foram a relação de obesidade e migrânea, fatores nutricionais, alergias alimentares e migrânea, e tratamento da migrânea. (LOSURDO, et al 2018;SLAVIN, et al, 2019;GRIAUZDAITĖ et al, 2020…”