Associations between Dopamine D4 Receptor Gene Variation with Both Infidelity and Sexual Promiscuity

Garcia, Justin R.; MacKillop, James; Aller, Edward L.; Merriwether, Ann; Wilson, David Sloan; Lum, J. Koji

doi:10.1371/journal.pone.0014162

Cited by 112 publications

(77 citation statements)

References 44 publications

(66 reference statements)

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“…In humans, individual differences in attachment style, fidelity, and sociosexuality are known to have a hereditary basis (26)(27)(28)(29). The degree to which variation in physiological mechanisms of attachment (30,31) and of sexual arousal (32,33) is shared between the sexes is not sufficiently known to predict whether between-sex correlations can be expected.…”

Section: Discussionmentioning

confidence: 99%

Female extrapair mating behavior can evolve via indirect selection on males

Forstmeier

Martin

Bolund

et al. 2011

Proc. Natl. Acad. Sci. U.S.A.

186

194

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In many species that form socially monogamous pair bonds, a considerable proportion of the offspring is sired by extrapair males. This observation has remained a puzzle for evolutionary biologists: although mating outside the pair bond can obviously increase the offspring production of males, the benefits of such behavior to females are less clear, yet females are known to actively solicit extrapair copulations. For more than two decades adaptionist explanations have dominated the discussions, yet remain controversial, and genetic constraint arguments have been dismissed without much consideration. An intriguing but still untested hypothesis states that extrapair mating behavior by females may be affected by the same genetic variants (alleles) as extrapair mating behavior by males, such that the female behavior could evolve through indirect selection on the male behavior. Here we show that in the socially monogamous zebra finch, individual differences in extrapair mating behavior have a hereditary component. Intriguingly, this genetic basis is shared between the sexes, as shown by a strong genetic correlation between male and female measurements of extrapair mating behavior. Hence, positive selection on males to sire extrapair young will lead to increased extrapair mating by females as a correlated evolutionary response. This behavior leads to a fundamentally different view of female extrapair mating: it may exist even if females obtain no net benefit from it, simply because the corresponding alleles were positively selected in the male ancestors.

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Section: Discussionmentioning

confidence: 99%

Female extrapair mating behavior can evolve via indirect selection on males

Forstmeier

Martin

Bolund

et al. 2011

Proc. Natl. Acad. Sci. U.S.A.

186

194

View full text Add to dashboard Cite

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“…Recent behavioral-genetic models confirm a common genetic factor for certain personality characteristics and risky sexual attitudes (Zietsch et al, 2010). Other analyses suggest genetic underpinnings for both novelty-seeking characteristics (Munafò, Yalcin, WillisOwen, & Flint, 2008) and a range of sexual attitudes and preferences (Ben Zion et al, 2006;Garcia et al, 2010;Halpern, Kaestle, Guo, & Hallfors, 2007).…”

Section: Male Bisexual Identity Sexual Curiosity and Sexual Arousalmentioning

confidence: 99%

“…Genotypes related to dopamine signaling predict personality characteristics such as sensation seeking and risk-taking (Lobo et al, 2010) and a wide range of novelty-seeking traits (Munafò et al, 2008). Dopamine-related genotypes also predict a variety of sexual characteristics, including promiscuity (Garcia et al, 2010), number of sex partners (Halpern et al, 2007) and sexual arousal (Ben Zion et al, 2006). Specific forms of dopamine receptor genes, related to sensation seeking, appear to be common in men with bisexual experiences (Hamer & Copeland, 1994).…”

Section: High Sexual Curiosity and Bisexual Arousalmentioning

confidence: 99%

Male bisexual arousal: A matter of curiosity?

Rieger

Rosenthal

Cash

et al. 2013

Biological Psychology

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“…Population differences in dopamine receptor (DRD4) genetic polymorphisms exist, with possible explanations advanced to account for those differences including genetic drift, adaptive migration, and mating behavior (Harpending and Cochran, 2002). A U.S. study found that polymorphisms in this same system were associated with differences in sexual promiscuity in a university sample (Garcia et al, 2010).…”

Section: Recent Genetic Genomic and Physiological Datamentioning

confidence: 99%

Evolution and human sexuality

Gray

2013

American J Phys Anthropol

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The aim of this review is to put core features of human sexuality in an evolutionary light. Toward that end, I address five topics concerning the evolution of human sexuality. First, I address theoretical foundations, including recent critiques and developments. While much traces back to Darwin and his view of sexual selection, more recent work helps refine the theoretical bases to sex differences and life history allocations to mating effort. Second, I consider central models attempting to specify the phylogenetic details regarding how hominin sexuality might have changed, with most of those models honing in on transitions from a possible chimpanzee-like ancestor to the slightly polygynous and long-term bonded sociosexual partnerships observed among most recently studied hunter-gatherers. Third, I address recent genetic and physiological data contributing to a refined understanding of human sexuality. As examples, the availability of rapidly increasing genomic information aids comparative approaches to discern signals of selection in sexuality-related phenotypes, and neuroendocrine studies of human responses to sexual stimuli provide insight into homologous and derived mechanisms. Fourth, I consider some of the most recent, large, and rigorous studies of human sexuality. These provide insights into sexual behavior across other national samples and on the Internet. Fifth, I discuss the relevance of a life course perspective to understanding the evolution of human sexuality. Most research on the evolution of human sexuality focuses on young adults. Yet humans are sexual beings from gestation to death, albeit in different ways across the life course, and in ways that can be theoretically couched within life history theory. Am J Phys Anthropol 57:94-118, 2013. V C 2013 Wiley Periodicals, Inc.The aim of this review is to put core features of human sexuality in an integrative, evolutionary light. Given the central importance of sexuality to the evolutionary imperative-reproductive success-there is strong theoretical impetus for understanding how evolution has shaped human sexuality in the past, and for how the influence of past selective forces continue to manifest in the present. For biological anthropologists, interdisciplinary social and biomedical scientists, and even wider audiences, questions about human sexuality can be among the most compelling and meaningful, another reason to try informing answers to fundamental questions of human sexuality with the most scientifically supported and current views. An understanding of human sexuality is central to topics as diverse as predicting the dynamics of a sexually transmitted infection (STI) outbreak to the reasons why people pour so much of their time and resources into mating effort. Human sexuality, as much as any other topical focus within biological anthropology, warrants ongoing evolutionary scrutiny.For several reasons, this is arguably an opportune time for providing a current overview of the evolution of human sexuality. For one, many of the foundati...

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Associations between Dopamine D4 Receptor Gene Variation with Both Infidelity and Sexual Promiscuity

Cited by 112 publications

References 44 publications

Female extrapair mating behavior can evolve via indirect selection on males

Female extrapair mating behavior can evolve via indirect selection on males

Male bisexual arousal: A matter of curiosity?

Evolution and human sexuality

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