Associations between clinical variables and quality of life in adults with cystic fibrosis

Gee, Louise; Abbott, Janice; Hart, Anna; Conway, S.P.; Etherington, C.; Webb, A K

doi:10.1016/j.jcf.2004.12.005

Cited by 78 publications

(113 citation statements)

References 23 publications

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“…Other studies have also described these correlations, especially in the domains related to physical functioning and to body and health perception, in adolescents and adults with altered FEV 1 . (21,26,27) In the literature, there are conflicting results regarding the correlation between pulmonary impairment and reported QoL in individuals with CF. This is due to the use of different types of questionnaires and to the age bracket…”

Section: Discussionmentioning

confidence: 99%

Avaliação da qualidade de vida de pacientes com fibrose cística por meio do Cystic Fibrosis Questionnaire

Cohen

Ribeiro

et al. 2011

J. bras. pneumol.

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Objective: To assess the quality of life (QoL) of patients with cystic fibrosis (CF) followed at a university referral center for CF. Methods: A cross-sectional study involving application of the Cystic Fibrosis Questionnaire (CFQ) and Shwachman score in CF patients between April of 2008 and June of 2009. Results: The sample consisted of 75 patients. The mean age was 12.5 ± 5.1 years (range, 6.1-26.4 years). The patients were divided into three groups by age in years: group I (< 12), , and III (≥ 14). The highest and lowest CFQ scores were for the nutrition domain in group III (89.3 ± 16.2) and the social domain in group II (59.5 ± 22.3), respectively. Groups I and III differed significantly regarding the treatment domain (p = 0.001). Regarding Shwachman scores, there were significant differences between patients scoring ≤ 70 and those scoring > 70 in the social (group I; p = 0.045), respiratory (group II; p = 0.053), and digestive (p = 0.042) domains. In group III, severity did not correlate with QoL. In groups I and II, patients with an FEV 1 < 80% of predicted did not differ from other patients for any CFQ domain. However, in group III, values for the following domains were significantly lower in patients with an Resultados:Participaram 75 pacientes, com média de idade de 12,5 ± 5,1 anos (variação: 6,1-26,4 anos). Os pacientes foram divididos em três grupos de acordo com a idade: grupo I (< 12 anos), II (12-14 anos) e III (≥ 14 anos). As pontuações mais altas e mais baixas no CFQ foram para o domínio alimentação do grupo III (89,3 ± 16,2) e para o domínio social no grupo II (59,5 ± 22,3), respectivamente. Houve uma diferença significativa no domínio tratamento entre os grupos III e I (p = 0,001). Pacientes com escore de Shwachman ≤ 70 apresentaram diferenças significativas em relação aos domínios social (grupo I; p = 0,045), respiratório (grupo II; p = 0,053) e digestivo (p = 0,042) quando comparados aqueles com escores > 70. No grupo III, não se observou associação entre gravidade e QV. Nos grupos I e II, não se observou diferenças entre os pacientes com VEF 1 < 80% do previsto e os demais pacientes em todos os domínios do CFQ. Entretanto, no grupo III, as médias dos pacientes com VEF 1 < 80% do previsto foram significativamente menores nos domínios físico (p = 0,012), imagem corporal (p = 0,031), respiratório (p = 0,023), emocional (p = 0,041) e papel social (p = 0,024). Conclusões: A avaliação da QV em pacientes com FC é importante, pois contribui para uma melhor aderência ao tratamento.Descritores: Fibrose cística; Qualidade de vida; Questionários.

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Section: Discussionmentioning

confidence: 99%

Avaliação da qualidade de vida de pacientes com fibrose cística por meio do Cystic Fibrosis Questionnaire

Cohen

Ribeiro

et al. 2011

J. bras. pneumol.

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“…This implies that patients with frequent chest symptoms are most likely to be anxious and experience exacerbations, 19 hospital readmission, and impaired quality of life. 19,20 The association between impaired quality of life, anxiety and depression, and hospital readmission may reflect the complexity of coping with multiple illnesses and the subsequent consequences of hospital readmission. This suggests the importance of an integrated disease management approach that includes counseling and psycho-educative plans such as written information on how individual CF patients self-manage their comorbid anxiety and depressive symptoms.…”

Section: Association Of Anxiety and Depressionmentioning

confidence: 99%

Relationship Between Anxiety, Depression, and Quality of Life in Adult Patients With Cystic Fibrosis

et al. 2012

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BACKGROUND:The impact of anxiety and depression on quality of life (QOL) in adult patients with cystic fibrosis (CF) is fully unknown. We investigated the prevalence and factors associated with anxiety and depression, including QOL, in adult CF patients. METHODS: One hundred twenty-one adult CF subjects, age > 18 years were recruited from our out-patient clinic. Participants self-completed the Hospital Anxiety Depression Scale and the Cystic Fibrosis Quality of Life Questionnaire (CF-QOL). Socio-demographic data and values for lung function were extracted from the medical notes. RESULTS: Mean ؎ SD age was 30 ؎ 8.8 years, and age ranged 18 -70 years. Forty (33%) were identified with anxiety symptoms, 20 (17%) with depressive symptoms. Factors related with depression were impaired QOL and low lung function. Anxiety was associated with difficulty in interpersonal relationships and severity of chest symptoms. The CF-QOL subdomains (physical functioning, social functioning, treatment issues, chest symptoms, emotional functioning, concerns for the future, interpersonal relationships, body image, future/career concerns, and total CF-QOL) were all significantly correlated with anxiety (P < .001) and with depression (P < .001), respectively. CONCLUSIONS: Anxiety and depressive symptoms are common in adult CF patients. They are associated with poorer QOL, low lung function, reduced physical functioning, and severity of chest symptoms. Therefore, routine screening for symptoms of anxiety and depression is a worthy endeavor, and those identified with elevated clinical symptoms should be referred to receive appropriate treatment.

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“…Gee et al 236 used the CFQoL questionnaire to examine associations between various clinical variables and QoL in 223 patients, and this was one of the few studies to provide any data on the effect of CFRD. Those with CFRD (49 patients) had lower FEV (mean 41% predicted, 25-75 percentile, range 30-59) than those without (mean 55%, range .…”

Section: Medline = 1064 Retrieved Embase = 1281 Retrievedmentioning

confidence: 99%

Screening for cystic fibrosis-related diabetes: a systematic review.

Waugh

Royle²,

Craigie³

et al. 2012

Health Technol Assess

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Associations between clinical variables and quality of life in adults with cystic fibrosis

Cited by 78 publications

References 23 publications

Avaliação da qualidade de vida de pacientes com fibrose cística por meio do Cystic Fibrosis Questionnaire

Avaliação da qualidade de vida de pacientes com fibrose cística por meio do Cystic Fibrosis Questionnaire

Relationship Between Anxiety, Depression, and Quality of Life in Adult Patients With Cystic Fibrosis

Screening for cystic fibrosis-related diabetes: a systematic review.

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